Results 31 to 40 of about 205,267 (312)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Transcriptome dynamics of rooting zone and aboveground parts of cuttings during adventitious root formation in Cryptomeria japonica D. Don

open access: yesBMC Plant Biology, 2018
Background Adventitious root formation is an essential physiological process for successful propagation of cuttings in various plant species. Because coniferous species are highly heterozygous, propagation of cuttings is of great practical use in ...
Yuki Fukuda   +6 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The Need for Perform ance Criteria in Evaluating the Durability of W ood Products

open access: yesForestist, 2008
Data generated İroni vvood-product durability evaluatioııs can be difficult to interpret. Standard metlıods used to evaluate the potential loııg-term durability of vvood products often provide little guidance on interpretation of test results ...
Stan Lebow   +3 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Bending performance of sugi cross-laminated timber (CLT) composed of different thickness laminae

open access: yesJournal of Wood Science
This study aims to examine the influence of lamina thickness on the bending performance of sugi cross-laminated timber (CLT). The lamina specimens measuring 20 mm, 30 mm and 40 mm thick × 115 mm wide, and the CLT specimens composed of 5-layer–5-ply of ...
Miyuki Nakagawa   +4 more
doaj   +1 more source

Grease, Oxygen, and Air Barrier Properties of Cellulose-Coated Copy Paper

open access: yesPolysaccharides
Cellulose nanomaterials have been demonstrated to be excellent barriers against grease, oxygen, and other vapors, but their implementation in packaging materials is challenging because of numerous technical and practical challenges.
Ronald Sabo   +7 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Regional haze four factor analysis, Columbia Forest Products

open access: yes, 2020
prepared for: Columbia Forest Products ; [prepared by: SLR].Title from PDF cover (viewed on May 25, 2021)."The Oregon Department of Environmental Quality (DEQ) identified the Facility as a significant source of regional haze precursor emissions to a ...

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