This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang +7 more
wiley +1 more source
Association of sleep disturbance during breast cancer treatment and left ventricular ejection fraction decline: a prospective cohort study. [PDF]
Szewczyk W +9 more
europepmc +1 more source
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source
Prospective Registry and Meta-Analysis of Particle Therapy for Hepatocellular Carcinoma: Clinical Outcomes and Real-World Impact. [PDF]
Mizumoto M +29 more
europepmc +1 more source
Advice note for a pre-registration inspection of an academy/free school/studio school/university technical college (UTC) : Eden Girls' School, Waltham Forest [PDF]
Paul Metcalf
openalex
Ce‐Doped Lignin‐Based Nanozyme with Heat‐Activated Hydrolase Activity
A novel Ce‐doped lignin‐based hydrolase nanozyme (Ce‐AL) is synthesized using Ce ions coordinated with aminated industrial lignin. The Ce‐AL effectively hydrolyzes phosphate ester bonds and protein amide bonds, maintain high activity at 100°C, and successfully fights bacteria biofilms.
Xin Liu +7 more
wiley +1 more source
The effect of personalized forest therapy programs on stress and obsessive-compulsive symptoms in patients with depression. [PDF]
Kim G +10 more
europepmc +1 more source
By engineering the PVA/H3PO4 ionic elastomer with optimized viscoelasticity and a height‐graded microstructure, the pressure sensor achieves a broad linear range up to 2000 kPa and a high sensitivity of 2.70 nF/kPa. These advancements underscore its strong potential for wearable electronics, including bio‐signal detection, health monitoring, and ...
Allen J. Cheng +13 more
wiley +1 more source
Web-Based Application of Simplified Machine Learning for Detecting Reduced LVEF From 12-Lead ECG. [PDF]
Kawakami H +6 more
europepmc +1 more source

