Results 181 to 190 of about 1,009,382 (298)

The Assembly of Tropical Dry Forest Tree Communities in Anthropogenic Landscapes: The Role of Chemical Defenses. [PDF]

open access: yesPlants (Basel), 2022
Bravo-Monzón ÁE   +7 more
europepmc   +1 more source

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

The Challenge of Handling Structured Missingness in Integrated Data Sources

open access: yesAdvanced Intelligent Discovery, EarlyView.
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson   +6 more
wiley   +1 more source

Contribution of Range-Wide and Short-Scale Chemical Soil Variation to Local Adaptation in a Tropical Montane Forest Tree. [PDF]

open access: yesEvol Appl
Arenas S   +8 more
europepmc   +1 more source

Prediction of Strength and CBR Characteristics of Chemically Stabilized Coal Gangue: ANN and Random Forest Tree Approach. [PDF]

open access: yesMaterials (Basel), 2022
Amin MN   +7 more
europepmc   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

Predicting Forest Tree Leaf Phenology Under Climate Change Using Satellite Monitoring and Population-Based Genomic Trait Association. [PDF]

open access: yesGlob Chang Biol
Pfenninger M   +9 more
europepmc   +1 more source

Growth-defense trade-offs shape population genetic composition in an iconic forest tree species. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Cope OL   +3 more
europepmc   +1 more source

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