The Assembly of Tropical Dry Forest Tree Communities in Anthropogenic Landscapes: The Role of Chemical Defenses. [PDF]
Bravo-Monzón ÁE +7 more
europepmc +1 more source
Advanced Experiment Design Strategies for Drug Development
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang +3 more
wiley +1 more source
Genetic Assignment at Different Geographical Levels: A Case Study in a Forest Tree Species (<i>Pinus pinaster</i> Ait.) Using SNP Markers. [PDF]
Olsson S +5 more
europepmc +1 more source
Common garden experiments reveal acquisitive strategies for responding to drought in seedlings of forest tree species: a commentary on 'Clinal variations in seedling traits and responses to water availability correspond to seed-source environmental gradients in a foundational dryland tree species'. [PDF]
Solé-Medina A, Ramírez-Valiente JA.
europepmc +1 more source
The Challenge of Handling Structured Missingness in Integrated Data Sources
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson +6 more
wiley +1 more source
Contribution of Range-Wide and Short-Scale Chemical Soil Variation to Local Adaptation in a Tropical Montane Forest Tree. [PDF]
Arenas S +8 more
europepmc +1 more source
Prediction of Strength and CBR Characteristics of Chemically Stabilized Coal Gangue: ANN and Random Forest Tree Approach. [PDF]
Amin MN +7 more
europepmc +1 more source
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Predicting Forest Tree Leaf Phenology Under Climate Change Using Satellite Monitoring and Population-Based Genomic Trait Association. [PDF]
Pfenninger M +9 more
europepmc +1 more source
Growth-defense trade-offs shape population genetic composition in an iconic forest tree species. [PDF]
Cope OL +3 more
europepmc +1 more source

