Results 221 to 230 of about 1,408,150 (349)
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Effect of Fertilization on the Performance of Adult Pinus pinea Trees. [PDF]
Loewe-Muñoz V +4 more
europepmc +1 more source
This study reveals the mechanism by which jasmonic acid (JA) regulates lycopene synthesis under light and dark conditions. In light, JA activates SlMYC2, which suppresses SlPIF1a and promotes SlPSY1 expression. In darkness, JA induces the acetyltransferase SlNATA1, which acetylates the dark‐accumulated SlPIF1a, thereby repressing SlPSY1 expression ...
Jiayi Xu +10 more
wiley +1 more source
Shifts in trait diversity across the range of an endemic treeline species in central Chile. [PDF]
Hernández C +3 more
europepmc +1 more source
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li +9 more
wiley +1 more source
Genetically distinct hantaviruses in two bat species in Panamá. [PDF]
Yamada K +16 more
europepmc +1 more source
Climate Change Threatens Micronutrient Density of European Winter Wheat
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao +17 more
wiley +1 more source
Geographic distribution of nematodes in the Atacama is associated with elevation, climate gradients and parthenogenesis. [PDF]
Villegas L +9 more
europepmc +1 more source

