Results 41 to 50 of about 567,732 (267)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Forma de guvernământ și puterea de revizuire constituțională (limitele revizuirii)

open access: yesRevista Transilvană de Ştiinţe Administrative, 2009
The 1991 Romanian Constitution has generated, soon after its adoption, numerous debates and has raised significant criticism. The 2003 amendment of the Constitution took place in the context of the adhesion process to the European Union and it was meant ...
Mircea CRISTE
doaj  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

INFLUENCE OF THE TYPE OF STATE SYSTEM ON CONSTITUTIONAL LEGISLATION: SOME ISSUES OF THEORY AND PRACTICE (by the example of the Russian Federation and Kazakhstan Republic)

open access: yesRussian Journal of Economics and Law, 2015
Objective: to study the basic laws of the constitutional law functioning of Kazakhstan Republic and the Russian Federation and its subjects in the system of law and legislation as an institutional phenomenon; to study the impact of government form on the
T. Z. Zhunuskanov
doaj  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Authorizing parliamentary control in the system of powers separation

open access: yesRussian Journal of Economics and Law, 2014
Objective: to determine the degree of influence of the party system on the powers separation by using analysis of implementation of authorizing parliamentary control in the countries with different governmental forms (presidential, mixed, parliamentary ...
E. V. Kovryakova
doaj  

The Effect of Government Programs on Urban Sprawl of Tehran [PDF]

open access: yesنشریه جغرافیا و برنامه‌ریزی, 2015
The urban sustainable development is economic efficiency, social justice and environmental preservation so one of the its important conditions is utilization from urban land, otherwise cities suffer from urban sprawl. So far, several models are presented
Mohammad Soleymani   +3 more
doaj  

Forms of Governance and the Size of Rent-Seeking [PDF]

open access: yesSSRN Electronic Journal, 2007
In this paper we present a model of an organization where agents can choose between productive and rent-seeking activities. We consider two governance institutions, single ownership and corporate governance or parliament rule. Applications include models of internal organization of a firm, of a kingdom ruled either by an absolute monarch or by the ...
openaire   +4 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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