Results 101 to 110 of about 17,704 (296)

An Experimental and Simulation Study on the Formability of Commercial Pure Titanium Foil

open access: yesMicromachines
In order to understand the formability of as-received tempered commercial pure titanium grade 2 foils (CP Ti Gr2) with a thickness of 38 µm, a series of micro limited dome height (µ-LDH) tests were conducted in quasi-static speed (0.01 mm/s) at room ...
Jenn-Terng Gau   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microstructure Evolution and Forming Characteristics of Post-Weld Composite Treatment of 6061 Aluminum Alloy Tailor Welded Blanks

open access: yesApplied Sciences
The mechanical properties and cross-sectional geometric dimensions of the fusion zone (FZ), heat affected zone (HAZ), and base metal (BM) of 6xxx series aluminum alloys are inconsistent after filler wire welding, which reduces the formability of aluminum
Xiaonan Dong, Gang Song, Liming Liu
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Drape and formability of nonwovens

open access: yes, 2005
Bending and shearing are fabric properties that are important for apparel drape and formability. Nonwovens typically have high resistance to shearing and bending resistance that is dependent on basis weight and thickness.
Moore, Mary Ann   +5 more
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Formability of Magnesium Alloys AZ80 and ZE10

open access: yes, 2014
Formability of two magnesium alloys, namely, AZ80 and ZE10, has been investigated. Both alloys were supplied with a thickness of 0.8 mm. The grain structure of the as-received AZ80 alloy showed dislocations, twins and second-phase particles and-/or ...
Satanin, V   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Improving Forgings Formability by Warm Complexing Processes

open access: yes, 2017
Hand-tool is one of the important products which are widely used in manufacturing industry as well as in human life. The torx is one kind of hand-tools which is considered as a case study in this research. There are two trial preforms designed to analyze
Wei Lin Chen   +3 more
core   +1 more source

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