Results 111 to 120 of about 17,704 (296)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Formability of a high-strength Al Mg6.8 type alloy sheet

open access: yes, 1998
Room temperature formability testing was performed on an AlMg6.8 type alloy sheet with a fully recrystallized structure (average grain diameter similar to 18 mu m) and after partial annealing with a retained deformed structure.
Milenković, V   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Formability of stainless steel tailored blanks

open access: yes, 2004
In a number of systematic tests, the formability of tailored blanks consisting of even and different combinations of AISI304 and AISI316 in thickness of 0.8 mm and 1.5 mm have been investigated. In order to analyse the formability of tailored blanks with
Olsen, Flemming Ove   +2 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Graph-Mining Algorithm for the Evaluation of Bond Formability

open access: yes, 2010
International audienceThe formability of a bond in a target molecule is a bond property related to the problem of finding a reaction that synthesizes the target by forming the bond: the easier this problem, the higher the formability.
Pennerath, Frédéric   +5 more
core   +1 more source

Studying the fracture surface of brass CuZn37 and aluminum 1100 and their relationship with formability in Single Point Incremental Forming

open access: yesFracture and Structural Integrity
Single Point Incremental Forming was conducted on Aluminum1100 and Brass CuZn37 to form a hyperbolic truncated pyramid with varying wall angles until the fracture occurs.
Marwa K. Qate�a   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The Effect of Varnishing and Soaking on Formability of the AW-5052-H28 Aluminium Alloy Sheets in Erichsen Cupping Test

open access: yesAdvances in Mechanical and Materials Engineering
This article presents the results of experimental tests on the stretch-forming ability of 0.21-mm-thick AW-5052-H28 aluminium alloy sheets used in the production of pull-off cups.
Krzysztof Żaba   +2 more
doaj   +1 more source

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