Results 1 to 10 of about 88 (88)
Novel insights into the roles of Cdc7 in response to replication stress
The FEBS Journal, Volume 290, Issue 12, Page 3076-3088, June 2023., 2023 Cdc7 and its regulator Dbf4 (Dbf4‐dependent kinase; DDK) is an essential complex due to its function in replication initiation. Evidence from yeast to human shows that Cdc7 is also required for a successful DNA damage response by coordinating multiple processes dealing with replication stress such as stalled fork protection, translesion synthesis (TLS),
Cristina González‐Garrido +1 more
wiley +1 more source
Use of infographics for facilitating learning of pharmacology in the nursing degree
Nursing Open, Volume 10, Issue 3, Page 1611-1618, March 2023., 2023 Abstract Aim To evaluate the impact of an educational intervention focused on teaching students to create infographics to improve pharmacology learning. Design This is a comparative study. Methods The population was 250 nursing students who had to create two infographics in groups related to the content that had been addressed in pharmacology in two ...
Alfonso Meneses‐Monroy +6 more
wiley +1 more source
The Plant Journal, Volume 113, Issue 6, Page 1330-1347, March 2023., 2023 SUMMARY The enzyme glutamine synthetase (EC 6.3.1.2) is mainly responsible for the incorporation of inorganic nitrogen into organic molecules in plants. In the present work, a pine (Pinus pinaster) GS1 (PpGS1b.2) gene was identified, showing a high sequence identity with the GS1b.1 gene previously characterized in conifers.
José Miguel Valderrama‐Martín +5 more
wiley +1 more source
MoBioTools: A toolkit to setup quantum mechanics/molecular mechanics calculations
Journal of Computational Chemistry, Volume 44, Issue 4, Page 516-533, February 5, 2023., 2023 Herein, we present MoBioTools, a toolkit to set up in an automatic manner QM/MM calculations on ensembles of geometries to be performed by several commonly used software packages for quantum chemistry calculations. The toolkit is characterized by the variety of situations it can be applied on, as well as the simplicity it can be employed with, by an ...
Gustavo Cárdenas +9 more
wiley +1 more source
Physiologia Plantarum, Volume 175, Issue 1, January/February 2023., 2023 Abstract Arbuscular mycorrhizal fungi may alleviate water stress in plants. Although several protection mechanisms have already been described, little information is available on how these fungi influence the hormonal response to water stress at an organ‐specific level.
David H. Fresno +2 more
wiley +1 more source
International Journal of Training and Development, Volume 26, Issue 4, Page 629-645, December 2022., 2022 Abstract Cooperations or transfers of the German technical and vocational education and training (TVET) system have taken place in different cultural contexts in recent decades. In Mexico, the so‐called Modelo Méxicano de Formación Dual has been adapted to Mexico's cultural conditions. Yet, it still seems to be largely unknown in society, the education
Claudia Hunink, Lydia Raesfeld
wiley +1 more source
A global analysis of factors predicting conservationists' values
People and Nature, Volume 4, Issue 5, Page 1339-1351, October 2022., 2022 Abstract There exists a wealth of philosophical, sociological and anthropological literature on environmental values; yet, few studies have investigated the values held by conservationists themselves, and how these shape the conservation movement. Here, we present the first global analysis of the relationships between conservationists' values and a ...
Rogelio Luque‐Lora +4 more
wiley +1 more source
Glia, Volume 70, Issue 9, Page 1734-1761, September 2022., 2022 Main Points Ventricular inflammation drives long‐lasting priming of hypothalamic microglia. Response of primed hypothalamic microglia to challenges such as HDF and obesity is increased. Past inflammatory events alter hypothalamus and energy balance regulation.
María del Mar Fernández‐Arjona +3 more
wiley +1 more source
A revised view on the evolution of glutamine synthetase isoenzymes in plants
The Plant Journal, Volume 110, Issue 4, Page 946-960, May 2022., 2022 SUMMARY Glutamine synthetase (GS) is a key enzyme responsible for the incorporation of inorganic nitrogen in the form of ammonium into the amino acid glutamine. In plants, two groups of functional GS enzymes are found: eubacterial GSIIb (GLN2) and eukaryotic GSIIe (GLN1/GS).
José Miguel Valderrama‐Martín +6 more
wiley +1 more source
Interleukin‐11 promotes lung adenocarcinoma tumourigenesis and immune evasion
Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.IL‐11 drives tumour progression and is linked to poor survival in lung adenocarcinoma patients, as well as an immunosuppressive tumour microenvironment. Antibody targeting of the IL‐11 receptor (IL‐11RA) shows significant anti‐tumour effects in a patient‐derived xenograft model highlighting IL‐11 as a compelling therapeutic target.
Cristina Cirauqui +25 more
wiley +1 more source