Results 61 to 70 of about 368,952 (258)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Characterizing Image Sets Using Formal Concept Analysis

open access: yesEURASIP Journal on Advances in Signal Processing, 2005
This article presents a new method for supervised image classification. Given a finite number of image sets, each set corresponding to a place of an environment, we propose a localization strategy, which relies upon supervised classification.
Zenou Emmanuel, Samuelides Manuel
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Toward a Broader Understanding: A Formal Concept Analysis of the Micropolitics of a School

open access: yesActa Paedagogica Vilnensia, 2018
[full article in English] The micropolitics of a school is one of the key factors that determine changes in member interactions in a learning organization and requires a careful study in order to create a favorable school environment.
Aida Kairienė
doaj   +1 more source

Monotone concepts for formal concept analysis

open access: yesDiscrete Applied Mathematics, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Deogun, Jitender S., Saquer, Jamil
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The algebraic structure of morphosyntactic features

open access: yesNordlyd: Tromsø University Working Papers on Language & Linguistics, 2015
The most common way of separating homophony from syncretism — which is a basic challenge for any inflectional analysis: to distinguish between accidental and systematic form-identity — is attributing only the latter to a coherent feature combination ...
Sebastian Bank
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Rule Acquisition in Formal Decision Contexts Based on Formal, Object-Oriented and Property-Oriented Concept Lattices

open access: yesThe Scientific World Journal, 2014
Rule acquisition is one of the main purposes in the analysis of formal decision contexts. Up to now, there have been several types of rules in formal decision contexts such as decision rules, decision implications, and granular rules, which can be viewed
Yue Ren   +3 more
doaj   +1 more source

Toward reliable machine learning with Congruity: a quality measure based on formal concept analysis. [PDF]

open access: yesNeural Comput Appl, 2023
De Maio C   +4 more
europepmc   +1 more source

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