Results 41 to 50 of about 338,726 (289)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Extension of Stein’s lemma derived by using an integration by differentiation technique

open access: yesExamples and Counterexamples, 2022
We extend Stein’s lemma for averages that explicitly contain the Gaussian random variable at a power. We present two proofs for this extension of Stein’s lemma, with the first being a rigorous proof by mathematical induction.
Konstantinos Mamis
doaj   +1 more source

Hydrodynamic equations for electrons in graphene obtained from the maximum entropy principle

open access: yes, 2013
The maximum entropy principle is applied to the formal derivation of isothermal, Euler-like equations for semiclassical fermions (electrons and holes) in graphene.
Barletti, Luigi
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The Complex Langevin method: When can it be trusted?

open access: yes, 2010
We analyze to what extent the complex Langevin method, which is in principle capable of solving the so-called sign problems, can be considered as reliable.
B. Helffer   +8 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Mean-field expansion in Bose-Einstein condensates with finite-range interactions

open access: yes, 2005
We present a formal derivation of the mean-field expansion for dilute Bose-Einstein condensates with two-particle interaction potentials which are weak and finite-range, but otherwise arbitrary.
Beliaev S. T.   +7 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Dowód matematyczny – argumentacja czy derywacja? – część II

open access: yesZagadnienia Filozoficzne w Nauce, 2011
In the first part of the paper, Azzouni’s derivation–indicator view was presented. In the second part it is analyzed in a detailed way. It is shown, that many problems arise, which cannot be explained in a satisfactory way in Azzouni’s theory, in ...
Krzysztof Wójtowicz
doaj  

Limiting the Number of Possible CFG Derivative Trees During Grammar Induction with Catalan Numbers

open access: yesMathematics
Grammar induction runs into a serious problem due to the exponential growth of the number of possible derivation trees as sentence length increases, which makes unsupervised parsing both computationally demanding and highly indeterminate.
Aybeyan Selim   +2 more
doaj   +1 more source

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