Results 41 to 50 of about 674,793 (310)
EDUCAŢIA DE GEN ÎN CONTEXT FORMAL-NONFORMAL-INFORMAL
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2021 În prezentul articol este abordată educația de gen. Constatările și concluziile sunt făcute în baza analizei unor experiențe practice, subiectul fiind explorat în context formal-nonformal-informal.
Valentina BODRUG-LUNGU
doaj
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Thinking About Political Education in Formal Education
Revista Electrónica Educare, 2018 The purpose of this essay is to share the reflections about the meaning of politics to be able to think, from there, of the potential of a kind of education capable of giving back to the subject the right to take the floor and act, to exercise the ...
Ana Corina Fernández Alatorre
doaj +1 more source
Migrant Children in Schools in Serbia – Barrier or Challenge for a New Beginning [PDF]
Демографија, 2018 The inclusion of migrant children into the formal education system of the Republic of Serbia represents a long-term project implemented by the Ministry of Education, Science and Technological Development with the support of international organizations ...
Ivana Đorđević +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Life Long Education: A Conceptual Debate
Seminar.net, 2009 This paper deals with the nature of a concept of lifelong education. Lifelong education can be provided through informal, formal and non-formal education processes.
Muhammad Javed Iqbal
doaj
"FORMAL" AND "NON-FORMAL" EDUCATION IN THE DIFFERENTIATION OF INTRINSIC PROPERTIES
Освітній дискурс, 2019 The article analyzes the definitions of "formal" and "non- formal" education as varieties of lifelong learning in the context of foreign and Ukrainian scholars. The meaningful field of "lifelong education" in the coordinates of interdisciplinary research
Volodymyr Slabko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source