Results 51 to 60 of about 858,441 (306)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Indonesian Journal of InstructionArtificial Intelligence (AI) literacy has become an essential competency for students in responding to rapid digital transformation across various fields.
Ahmad Ahmad +3 more
doaj +3 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The Community Empowerment Through Social and Educational Institutions
Jurnal Pendidikan Humaniora, 2018 : The purpose of this study is to explore the role of social and educational institutions in Bajulmati in the process of community empowerment. This research uses a qualitative approach.
Bayu Adi Laksono
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A sustainable future - the recent goal in education
Sustainability has become a serious goal of education, and the principles of sustainability have started to be integrated into the secondary education curricula.
Mandrea, Teodora
core +1 more source
Bridging the Gap between Formal Education and Informal Learning via Science Centre Pedagogy [PDF]
, 2014 The role of informal learning is increasing in the modern societies. This phenomenon is closely related to the growing impact of science and technology on our everyday lives. Lifelong learning needs new practical forms.
Salmi, Hannu
core
The Causes of Indoctrination in Formal and Informal Education Systems and Provide Solutions Compatible with Islamic Culture [PDF]
علوم تربیتی از دیدگاه اسلام, 2016 The purpose of this research was to explain and critique the causes of indoctrination in formal and informal education systems and to offer solutions that are compatible with Islamic culture.
hassan bagherinia, Saeed Shakuri Moghani
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source