Results 71 to 80 of about 858,441 (306)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Managing Formal, Non-Formal and Informal Economic Education [PDF]

Revista de Management Comparat International, 2013
If we consider how to effectively deal with economic education, we should start with the questions that entrepreneurs ask themselves when they start a business. Their goal is to make it profitable.
Monica Elisabeta PĂDURARU
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Digital Education for Sustainable Development in Non-Formal Education in Germany and COVID-19-Induced Changes

, 2022
Digital media increasingly transform daily routines as well as everyday actions and working environments, including education. Apps, games, computer programs, and social media, etc. can support and improve learning processes.
Florian Kohler, Kohler, Florian, Rochholz, Fiona, Kuthe, Alina, Fiona Rochholz, Alina Kuthe, Siegmund, Alexander, Alexander Siegmund   +7 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Improving Students’ Learning Aspirations Beyond Post-Primary Education : A First Account of Two Non-Formal Education Programmes in Middle-Income Countries

, 2014
Non-formal education programmes are active in a number of developing countries. These programmes offer vulnerable students an opportunity to pursue their education although they were excluded for various reasons from the formal education systems.
Lasselle, Laurence, Arico, Fabio Riccardo, Thampanishvong, Kannika   +2 more
core  

Development of Smart Link Book as a Medium for Interaction Between Special School Institutions and Parents Through User Centered Design [PDF]

E3S Web of Conferences
By redesigning linking books, this study seeks to enhance the user-communication experience (UX) between school-aged children with special needs (SLB) and their parents.
Listyaningrum R. Anggia, Nur Hidayat Wahyu, Ediyanto, Nur Iswara Luthansyah, Dicky Maulana Irwanto Lalu, Wahiza Binti Abdul Wahat Nor   +5 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Life Long Education: A Conceptual Debate

Seminar.net, 2009
This paper deals with the nature of a concept of lifelong education. Lifelong education can be provided through informal, formal and non-formal education processes.
Muhammad Javed Iqbal
doaj  

School education amid crisis: a secondary data analysis of cyclone Amphan and COVID-19 in North & South 24 Parganas, West Bengal

Discover Global Society
West Bengal in India is one of the worst impacted states by the cyclones. The first super cyclone after the 1999 super cyclone was in May 2020, called cyclone Amphan, which devastated West Bengal to its core, especially the North 24 Parganas and South 24
Tisha Goswami, Zafar Tabrez
doaj   +1 more source