Results 71 to 80 of about 1,501,622 (351)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Tensor Networks and Quantum Error Correction

, 2014
We establish several relations between quantum error correction (QEC) and tensor network (TN) methods of quantum many-body physics. We exhibit correspondences between well-known families of QEC codes and TNs, and demonstrate a formal equivalence between ...
Ferris, Andrew J., Poulin, David
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Kneser-Hecke-operators in coding theory

, 2006
The Kneser-Hecke-operator is a linear operator defined on the complex vector space spanned by the equivalence classes of a family of self-dual codes of fixed length.
Nebe, Gabriele
core   +2 more sources

YAPA: A generic tool for computing intruder knowledge [PDF]

, 2009
Reasoning about the knowledge of an attacker is a necessary step in many formal analyses of security protocols. In the framework of the applied pi calculus, as in similar languages based on equational logics, knowledge is typically expressed by two ...
B. Blanchet, B. Blanchet, G. Lowe, H. Comon-Lundh, M. Abadi, M. Abadi, M. Abadi, M. Baudet, M. Baudet, S. Anantharaman, V. Cortier, V. Cortier, Y. Chevalier   +12 more
core   +5 more sources

Marriage Parties, Rules, and Contract Expressions in Qur’an Translations: A Critical Analysis

Open Cultural Studies
Marriage is one of many important topics discussed in the Qur’an and is a vital component of the customs and traditions of every community. This study aims to qualitatively investigate the procedures employed by classical and recent translators in ...
AbuAlkheir Haneen, Farghal Mohammed, Haider Ahmad S.   +2 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

p-adic deformation of algebraic cycle classes [PDF]

, 2013
We study the p-adic deformation properties of algebraic cycle classes modulo rational equivalence. We show that the crystalline Chern character of a vector bundle lies in a certain part of the Hodge filtration if and only if, rationally, the class of the
Bloch, Spencer, Esnault, Hélène, Kerz, Moritz   +2 more
core   +2 more sources