Results 61 to 70 of about 1,456,568 (303)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Metaphysical Equivalence: How formal concepts of theory equivalence inform metaphysical debates [PDF]

Concepts of theoretical equivalence aim to capture what it means that theories “say the same thing” or “have the same” content. In the context of formal theories, there are precise formal concepts that explicate ways in which formalized theories are ...
Schobinger, Timo
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

A robust graph-based approach to observational equivalence [PDF]

Logical Methods in Computer Science
We propose a new step-wise approach to proving observational equivalence, and in particular reasoning about fragility of observational equivalence. Our approach is based on what we call local reasoning.
Dan R. Ghica, Koko Muroya, Todd Waugh Ambridge   +2 more
doaj   +1 more source

Fuzzy Implication and Functional Dependency on Formal Context

Jurnal Matematika Integratif, 2020
Fuzzy formal concept analysis(FFCA) is a development of formal concept analysis(FCA) with the degree of relation between objects and attributes. Using FCA approach, we will investigate the condition logical implication for fuzzy functional dependency. We
Mohammad Deni Akbar, Yoshihiro Mizoguchi
doaj   +1 more source

Formalizing equivalences without tears

CoRR
v4: To appear in the TYPES 2024 post ...
openaire   +5 more sources

Notes on providing a formal definition of equivalence

, 2010
This paper presents an outline of the definition of equivalence in mathematics. The supporting language of set theory is informally presented. Definitions are provided for Cartesian product, relation and equivalence relation.
Gabrielle Martino
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Artificial Examples of Empirical Equivalence [PDF]

, 2013
In this paper I analyze three artificial examples of empirical equivalence: van Fraassen’s alternative formulations of Newton’s theory, the Poincaré-Reichenbach argument for the conventionality of geometry; and predictively equivalent ‘systems of the ...
Acuña, Pablo
core  

Definable Categorical Equivalence [PDF]

, 2018
This paper aims to provide a new criterion of formal equivalence of theories that is suitable for being supplemented with preservation conditions concerning interpretation.
Hudetz, Laurenz
core   +1 more source