Results 71 to 80 of about 39,507 (262)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Adaptation and content validity of the Brazilian version of the Mental Health Literacy questionnaire [PDF]
Revista Brasileira de EnfermagemObjectives: to perform cross-cultural adaptation and content validity of the Mental Health Literacy questionnaire into Brazilian Portuguese. Methods: a validity study developed according to the following stages: (1) assessment of conceptual and item ...
Wanderson Carneiro Moreira +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
On the equivalence of translations of Abai’s poetic text
Неофилология, 2020 We consider the equivalence of source and translation texts. Currently, various ways to achieve the adequacy of texts are being studied, which proves the relevance of this problem.
K. M. Abisheva +2 more
doaj +1 more source
Formal Equivalence Analysis [PDF]
Proceedings of the 2019 Conference of the International Fuzzy Systems Association and the European Society for Fuzzy Logic and Technology (EUSFLAT 2019), 2019 Francisco José Valverde Albacete +3 more
openaire +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Formal Verification of Transcompiled Mobile Applications Using First-Order Logic
TechnologiesThe increasing interest in automated code conversion and transcompilation—driven by the need to support multiple platforms efficiently—has raised new challenges in verifying that translated codes preserve the intended behaviors of the originals. Although
Ahmad Ahmad Muhammad +8 more
doaj +1 more source
MATHEMATICS OF KIN- AND GROUP-SELECTION: FORMALLY EQUIVALENT? [PDF]
Evolution, 2010 Evolutionary game theory is a general mathematical framework that describes the evolution of social traits. This framework forms the basis of many multilevel selection models and is also frequently used to model evolutionary dynamics on networks. Kin selection, which was initially restricted to describe social interactions between relatives, has also ...
openaire +3 more sources