Results 41 to 50 of about 1,997,974 (296)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

The intonation of South Asian languages: towards a comparative analysis [PDF]

open access: yes, 2016
South Asia has long been considered a region of widespread convergence in phonology, morphology, and syntax. While these claims have not explicitly been extended to intonation in previous work, researchers such as Fe?ry (2010) have suggested that ...
Khan, Sameer ud Dowla
core   +1 more source

Formal Verification of Security Protocol Implementations: A Survey [PDF]

open access: yes, 2014
Automated formal verification of security protocols has been mostly focused on analyzing high-level abstract models which, however, are significantly different from real protocol implementations written in programming languages.
Pironti, Alfredo   +3 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

A Component-Based Formal Language Workbench [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2019
The CBS framework supports component-based specification of programming languages. It aims to significantly reduce the effort of formal language specification, and thereby encourage language developers to exploit formal semantics more widely.
Peter D. Mosses
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Verb Root Allomorphy in Indo-Aryan Languages [PDF]

open access: yes
This paper aims to theoretically describe the phonological basis for the systematic verb root allomorphy seen in some of the Indo-Aryan languages. To highlight the similarities and differences in allomorphy patterns, three languages, Bangla, Hindi and ...
Sanyal, Paroma
core   +1 more source

Applying Automated Model Extraction for Simulation and Verification of Real-Life SDL Specification With Spin

open access: yesIEEE Access, 2017
Formally defined Specification and Description Language (SDL) is used for the design and specification of complex safety-critical systems. Each change in the specification of the product should be immediately checked formally against the requirements ...
Bostjan Vlaovic   +2 more
doaj   +1 more source

Pacific Languages [PDF]

open access: yes, 2018
Almost one-quarter of the world's languages are (or were) spoken in the Pacific, making it linguistically the most complex region in the world. Although numerous technical books on groups of Pacific or Australian languages have been published, and ...
Lynch, John
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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