Results 51 to 60 of about 864,679 (285)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Efficient Performative Actions for E-Commerce Agents

open access: yesApplied Computer Systems, 2020
The foundational features of multi-agent systems are communication and interaction with other agents. To achieve these features, agents have to transfer messages in the predefined format and semantics.
Qasim Awais   +3 more
doaj   +1 more source

Formal Languages in Dynamical Systems [PDF]

open access: yes, 1993
We treat here the interrelation between formal languages and those dynamical systems that can be described by cellular automata (CA). There is a well-known injective map which identifies any CA-invariant subshift with a central formal language.
Troll, G.
core   +1 more source

Formal languages and enumeration

open access: yesJournal of Combinatorial Theory, Series A, 1978
AbstractWe present a theory of generating functions in countably many non-commuting variables. This generalizes the theory of context free languages. Applications are given to compositions of a number, rooted planar tree, dissected polygons, and the theory of simple random walks.
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

One Approach to the Problem Solution of Specialized Software Development for Subject Search

open access: yesProceedings of the International Conference on Applied Innovations in IT, 2016
In the article relevance of system development for subject search using computational linguistics is considered. The basic principles of system functioning are defined.
Dmitriy Grinchenkov   +2 more
doaj   +1 more source

Analogy and Formal Languages

open access: yesElectronic Notes in Theoretical Computer Science, 2004
AbstractIn this paper, we advocate a study of analogies between strings of symbols for their own sake. We show how some sets of strings, i.e., some formal languages, may be characterized by use of analogies. We argue that some preliminary “good properties” obtained may plead in favour of the use of analogy in the study of formal languages in ...
openaire   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Mathematical logic in the human brain: syntax. [PDF]

open access: yesPLoS ONE, 2009
Theory predicts a close structural relation of formal languages with natural languages. Both share the aspect of an underlying grammar which either generates (hierarchically) structured expressions or allows us to decide whether a sentence is ...
Roland Friedrich, Angela D Friederici
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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