Results 41 to 50 of about 1,932,015 (306)
The Age-of-Information Distribution in Slotted ALOHA
IEEE AccessAge-of-Information (AoI) is a new performance metric for critical networked cyber-physical systems (CPS), where performance depends on how quickly fresh data is received in update packets.
Dieter Fiems, Alexey Vinel
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IEEE Access, 2021 Cause-consequence Diagram (CCD) is widely used as a deductive safety analysis technique for decision-making at the critical-system design stage. This approach models the causes of subsystem failures in a highly-critical system and their potential ...
Mohamed Abdelghany, Sofiene Tahar
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied Sciences, 2021 Models@runtime (models at runtime) are based on computation reflection. Runtime models can be regarded as a reflexive layer causally connected with the underlying system. Hence, every change in the runtime model involves a change in the reflected system,
Mohammed Mounir Bouhamed +4 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Formal Methods and Validation Techniques for Ensuring Automotive Systems Security
Information, 2023 The increasing complexity and connectivity of automotive systems have raised concerns about their vulnerability to security breaches. As a result, the integration of formal methods and validation techniques has become crucial in ensuring the security of ...
Moez Krichen
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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FORMAL METHODS OF EXPERT ESTIMATIONS
Статистика и экономика, 2016 This article series discusses formal methods of expert assessments. Usingthe Delphi method helps to formalize theprocedures for the collection, compilationand analysis of the views of specialists inorder to convert them into a form most convenient for ...
Tea Ya. Danelyan
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source