Results 41 to 50 of about 4,569,836 (278)
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges +12 more
wiley +1 more source
The Age-of-Information Distribution in Slotted ALOHA
Age-of-Information (AoI) is a new performance metric for critical networked cyber-physical systems (CPS), where performance depends on how quickly fresh data is received in update packets.
Dieter Fiems, Alexey Vinel
doaj +1 more source
Models@runtime (models at runtime) are based on computation reflection. Runtime models can be regarded as a reflexive layer causally connected with the underlying system. Hence, every change in the runtime model involves a change in the reflected system,
Mohammed Mounir Bouhamed +4 more
doaj +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Formal Methods and Validation Techniques for Ensuring Automotive Systems Security
The increasing complexity and connectivity of automotive systems have raised concerns about their vulnerability to security breaches. As a result, the integration of formal methods and validation techniques has become crucial in ensuring the security of ...
Moez Krichen
doaj +1 more source
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Comparison of Tree-Sibling Time Consistent Phylogenetic Networks Is Graph Isomorphism-Complete
Several polynomial time computable metrics on the class of semibinary tree-sibling time consistent phylogenetic networks are available in the literature; in particular, the problem of deciding if two networks of this kind are isomorphic is in P.
Gabriel Cardona +3 more
doaj +1 more source
FORMAL METHODS OF EXPERT ESTIMATIONS
This article series discusses formal methods of expert assessments. Usingthe Delphi method helps to formalize theprocedures for the collection, compilationand analysis of the views of specialists inorder to convert them into a form most convenient for ...
Tea Ya. Danelyan
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

