Results 41 to 50 of about 4,569,836 (278)

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges   +12 more
wiley   +1 more source

The Age-of-Information Distribution in Slotted ALOHA

open access: yesIEEE Access
Age-of-Information (AoI) is a new performance metric for critical networked cyber-physical systems (CPS), where performance depends on how quickly fresh data is received in update packets.
Dieter Fiems, Alexey Vinel
doaj   +1 more source

Models@Runtime: The Development and Re-Configuration Management of Python Applications Using Formal Methods

open access: yesApplied Sciences, 2021
Models@runtime (models at runtime) are based on computation reflection. Runtime models can be regarded as a reflexive layer causally connected with the underlying system. Hence, every change in the runtime model involves a change in the reflected system,
Mohammed Mounir Bouhamed   +4 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Formal Methods and Validation Techniques for Ensuring Automotive Systems Security

open access: yesInformation, 2023
The increasing complexity and connectivity of automotive systems have raised concerns about their vulnerability to security breaches. As a result, the integration of formal methods and validation techniques has become crucial in ensuring the security of ...
Moez Krichen
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Comparison of Tree-Sibling Time Consistent Phylogenetic Networks Is Graph Isomorphism-Complete

open access: yesThe Scientific World Journal, 2014
Several polynomial time computable metrics on the class of semibinary tree-sibling time consistent phylogenetic networks are available in the literature; in particular, the problem of deciding if two networks of this kind are isomorphic is in P.
Gabriel Cardona   +3 more
doaj   +1 more source

FORMAL METHODS OF EXPERT ESTIMATIONS

open access: yesСтатистика и экономика, 2016
This article series discusses formal methods of expert assessments. Usingthe Delphi method helps to formalize theprocedures for the collection, compilationand analysis of the views of specialists inorder to convert them into a form most convenient for ...
Tea Ya. Danelyan
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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