Results 61 to 70 of about 14,914,060 (244)

A Formal and Quantifiable Log Analysis Framework for Test Driving of Autonomous Vehicles

open access: yesSensors, 2020
We propose a log analysis framework for test driving of autonomous vehicles. The log of a vehicle is a fundamental source to detect and analyze events during driving.
Kyungbok Sung   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Research challenges and future perspectives for e-assessment technologies in higher education

open access: yesi-com
E-assessment technologies have rapidly evolved in higher education, transforming the evaluation of learning outcomes and the delivery of feedback to students and educators.
Striewe Michael   +2 more
doaj   +1 more source

Teaching Formal Models of Concurrency Specification and Analysis

open access: yesМоделирование и анализ информационных систем, 2015
There is a widespread and rapidly growing interest to the parallel programming nowadays. This interest is based on availability of supercomputers, computer clusters and powerful graphic processors for computational mathematics and simulation. MPI, OpenMP,
N. V. Shilov
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Computational search for hypotheses concerning the endocannabinoid contribution to the extinction of fear conditioning

open access: yesFrontiers in Computational Neuroscience, 2013
Fear conditioning, in which a cue is conditioned to elicit a fear response, and extinction, in which a previously conditioned cue no longer elicits a fear response, depend on neural plasticity occurring within the amygdala.
Thomas eAnastasio
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Exploring the contribution of estrogen to amyloid-beta regulation:a novel multifactorial computational modeling approach

open access: yesFrontiers in Pharmacology, 2013
According to the amyloid hypothesis, Alzheimer Disease results from the accumulation beyond normative levels of the peptide amyloid-β (Aβ). Perhaps because of its pathological potential, Aβ and the enzymes that produce it are heavily regulated by the ...
Thomas J. Anastasio
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Non-Negotiated Implicit ETSI VAM Clustering

open access: yesIEEE Access
Including Vulnerable Road Users (VRUs) such as pedestrians and cyclists in Cooperative Intelligent Transport Systems (C-ITS) is key to improving road safety, but it also increases the number of active communication nodes and, as a result, the channel ...
Felipe E. Valle   +5 more
doaj   +1 more source

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