Results 71 to 80 of about 34,882,646 (291)

Proving Properties of Discrete-Valued Functions Using Deductive Proof: Application to the Square Root

open access: yesМоделирование и анализ информационных систем, 2019
For many years, automotive embedded systems have been validated only by testing. In the near future, Advanced Driver Assistance Systems (ADAS) will take a greater part in the car’s software design and development.
Vassil Todorov   +3 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Formal Research Methods in Political Science and Comparative Politics: The Prospects of MGIMO-University Political Science School

open access: yesСравнительная политика, 2015
The article is devoted to the peculiarities of the formal research methods in political science and the use of such methods in Russian comparative political and international studies, in particular at MGIMO-University.
Ivan Nikolaevich Timofeyev
doaj   +1 more source

Evaluating the suitability of state‐based formal methods for industrial deployment

open access: yesSoftware, Practice & Experience, 2018
After a number of success stories in safety‐critical domains, we are starting to witness applications of formal methods in contemporary systems and software engineering.
A. Mashkoor   +2 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Decision Support Within Digital Twins in Manufacturing Ecosystems: A Review

open access: yesIET Collaborative Intelligent Manufacturing
The dynamic nature of manufacturing and evolving customer demands require agile adaptation within Manufacturing Ecosystems—interconnected networks of enterprises and institutions collaborating to develop market—oriented solutions.
Lucía Gálvez del Postigo Gallego   +3 more
doaj   +1 more source

Survey on Learning-Based Formal Methods: Taxonomy, Applications and Possible Future Directions

open access: yesIEEE Access, 2020
Formal methods play an important role in testing and verifying software quality, especially in modern society with rapid technological updates.
Fujun Wang   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Towards Realising FollowMe User Profiles for Macro-Intelligent Environments

open access: yesComputers, 2013
In this paper, we introduce the concept of a Large-Scale Intelligent Environment (LSIE) and provide an introduction to the use of bigraphs as a formal method for description and modelling.
Luke Whittington   +3 more
doaj   +1 more source

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