Results 31 to 40 of about 210,142 (295)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Arc Spaces and Rogers-Ramanujan Identities [PDF]
Discrete Mathematics & Theoretical Computer Science, 2011 Arc spaces have been introduced in algebraic geometry as a tool to study singularities but they show strong connections with combinatorics as well. Exploiting these relations we obtain a new approach to the classical Rogers-Ramanujan Identities.
Clemens Bruschek +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Researches in MathematicsWe propose an algorithm for expanding a formal triple power series into a three-dimensional corresponding to this series associated continued fraction, which generalized one of the simplest algorithms for expanding a formal power series into a ...
Kh.Yo. Kuchminska, R.M. Deyneka
doaj +1 more source
Distances in random Apollonian network structures [PDF]
Discrete Mathematics & Theoretical Computer Science, 2008 In this paper, we study the distribution of distances in random Apollonian network structures (RANS), a family of graphs which has a one-to-one correspondence with planar ternary trees. Using multivariate generating functions that express all information
Olivier Bodini +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
On the formal power series of involutory functions [PDF]
Enumerative Combinatorics and Applications, 2023 Alfred Schreiber
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FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source
On a q—Analog of a Singularly Perturbed Problem of Irregular Type with Two Complex Time Variables
Mathematics, 2019 The analytic solutions of a family of singularly perturbed q-difference-differential equations in the complex domain are constructed and studied from an asymptotic point of view with respect to the perturbation parameter.
Alberto Lastra, Stéphane Malek
doaj +1 more source