Results 81 to 90 of about 2,768,927 (306)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Contingent Control and Wild Moments: Conducting Psychiatric Evaluations in the Home
Social Inclusion, 2019 When social control and social service workers go into the field, into the “native habitat” of some problem, a variety of tacit structures and controls that mark office work with its standardized documents and formal meetings are weakened or absent ...
Robert M. Emerson, Melvin Pollner
doaj +1 more source
Changing the Course of AIDS: Peer Education in South Africa and Its Lessons for the Global Crisis [PDF]
, 2009 [Excerpted from the Foreward by Charles Deutsch, Sc.D.] David Dickinson asks the question: How can we inject into the busy, distracted, difficult lives of the least educated and poorest among us the opportunity, and eventually the habit, to think ...
Dickinson, David
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in AgronomyAdoption rates of agroecological farming practices remain low amongst European farmers and vary from country to country, despite European or national policies aimed at achieving ‘sustainable agriculture’.
Antonio Paparella +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Why forums? An empirical analysis into the facilitating factors of carding forums
, 2013 Over the last decade, the nature of cybercrime has transformed from naive vandalism to profit-driven, leading to the emergence of a global underground economy. A noticeable trend which has surfaced in this economy is the repeated use of forums to operate
Shadbolt, Nigel +2 more
core
Simulation and formal verification of industrial systems controllers [PDF]
, 2008 Actually, the safety control is one of the most important aspects studied by the international researchers, in the field of design and development of automated production systems due to social (avoid work accidents, ...), economics (machine stop time ...
Campos, J. Creissac +4 more
core
Gender and crime: from exclusión to criminalization [PDF]
, 2019 La desigualdad de poder entre hombres y mujeres, producto de una socialización dicotómica y jerárquica, que constituye el imaginario de la sociedad patriarcal, trae como consecuencia que la mujer se vea adscrita a unas conductas estereotipadas, de tal ...
Revelles Carrasco, María
core +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source