Results 61 to 70 of about 2,768,927 (306)

Managing Cartels: how Cartel Participants Create Stability in the Absence of law [PDF]

open access: yes, 2016
Firms enter cartels (e.g. price-fixing; bid-rigging) in order to control market uncertainties and gain collusive profits, but face challenges in controlling the cartel itself.
Jaspers, J.D.
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Paying for Crimes and Earning Heaven. Daily Life of Imprisoned Women at “El Buen Pastor” Penitentiary 1890-1929.

open access: yesHistoria y Memoria, 2015
During the period of Colombian conservative hegemony, “El Buen Pastor” prison, in Bogotá, provides an illustration of penitentiary politics, as well as the formal and informal mechanisms of social control at the time, gathered in a single institution. In
July Andrea García Amézquita
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Encounters between security guards and young people: the extent and biases of formal social control

open access: yesPolicing and Society, 2014
There is a distinct lack of knowledge about how the rise of private security relates to young people in adversarial encounters. Prior studies suggest that the policing of young people by police is a common occurrence and social biases exist. However, policing of young people by private security guards has gained much less attention.
Saarikkomäki Elsa, Kivivuori Janne
openaire   +3 more sources

Eficacia de la ley penal como forma de control social formal en Chile [PDF]

open access: yes, 2008
60 p.La eficacia del derecho penal se ha ido atenuando en el tiempo, ello como una falta de adecuación temporal, llegando incluso a ser considerada ineficaz para el modelo de sociedad vigente, ya que la ley penal debe ser un reflejo de la identidad ...
Fernandoy Abarca, Anibal Fernando   +1 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Management control of supplier relationships in manufacturing: a case study in the automotive industry. [PDF]

open access: yes
This paper studies management control design of supplier relationships in manufacturing, a supply chain phase currently under-explored. Compared to supplier relations during procurement and R&D, which research found to be governed by a combination of ...
Pernot, Eli, Roodhooft, Filip
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Master Servant Relationships in the Eastern Cape: the 1820 Settlement

open access: yesAfrican Studies Quarterly, 2021
This article is about the rebellious behavior of the servant class and the consequent threat it posed to the established social order in the 1820 settlement.
Amina Marzouk Chouchene
doaj  

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