Results 171 to 180 of about 990,468 (303)

Computational Study of Gas-Phase Reactions to Produce Sulfite Esters: A New Class of Sulfur Containing Molecules in the Atmosphere? [PDF]

J Phys Chem Lett
Daub CD, Kumar A, Rissanen M.
europepmc   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Beyond Direct Two-Electron Oxidation: High-Potential Formaldehyde Oxidation on Palladium Still Generates Hydrogen Atoms. [PDF]

J Am Chem Soc
Li R, Li Y, Hu X, Gao T, Sun Y.
europepmc   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Screening a thermotolerant <i>Komagataella phaffii</i> strain with methanol cross-tolerance and the associated physiological and transcriptional responses. [PDF]

Synth Syst Biotechnol
Li C, Jiang T, Bo Y, Lu Z, Zhou Y, Zhang G.   +5 more
europepmc   +1 more source

Ru‐Doping‐Engineered Oxygen Vacancies in MoO3‐x Nanostructured Films With Ultrahigh Capacitance for Flexible Asymmetric Supercapacitors

Advanced Science, EarlyView.
Ru‐doping‐induced defect engineering enables freestanding Ru–MoO3‐x flexible films with enriched oxygen vacancies, modulated band structure, and enhanced charge transport. The optimized electrode delivers ultrahigh capacitance approaching the theoretical limit of MoO3, while assembled asymmetric supercapacitors exhibit high energy density, wide‐voltage
Xiaoqing Bin, Minhao Sheng, Norman C.‐R. Chen, Xiangyang Liu, Yingji Zhao, Yingyi Liao, Wenxiu Que, Yusuke Asakura, Yusuke Yamauchi   +8 more
wiley   +1 more source

Excess folate elevates formaldehyde genotoxicity in cell lines but not in mice or humans. [PDF]

EMBO Mol Med
Mellor C, James BT, Azad S, Kosmeder EP, Purello CT, Singh M, Simon V, Cheng NW, Niedermaier J, Burgos-Barragan G, Blenis JO, Mato AR, Field MS, Wang M.   +13 more
europepmc   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

NRF2 coordinates cystine import and glutathione use to sustain ferroptosis resistance and formaldehyde tolerance in cancer. [PDF]

Sci Adv
Morellato AE, Alquezar-Artieda N, Guerrero-Maldonado A, Singh R, Beja L, Umansky C, Perich-Pallaruelo L, Pellicer M, Fernandez-Deu P, Aira N, Bourached-Silva N, Chorostecki U, Jones DJL, Roué G, Hopkinson RJ, Pontel LB.   +15 more
europepmc   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source