Results 51 to 60 of about 990,468 (303)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Formaldehyde and Formaldehyde-Releasers
, 2012 This chapter in Kanerva’s Occupational Dermatology, 4th edition (2024), discusses contact allergy to and allergic contact dermatitis from formaldehyde and formaldehyde-releasers. Formaldehyde has many applications, which are shown in tabular format in this publication. However, it is a ubiquitous and important allergen.
de Groot, A.C., Flyvholm, Mari-Ann
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Genetic engineering of baker’s and wine yeasts using formaldehyde hyperresistance-mediating plasmids [PDF]
, 2009 Yeast multi-copy vectors carrying the for maldehyde-resistance marker gene SFA have proved to be a valuable tool for research on industrially used strains of Saccharomyces cerevisiae.
Schmidt, Martin +3 more
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Estimating European volatile organic compound emissions using satellite observations of formaldehyde from the Ozone Monitoring Instrument [PDF]
, 2010 Emission of non-methane Volatile Organic Compounds (VOCs) to the atmosphere stems from biogenic and human activities, and their estimation is difficult because of the many and not fully understood processes involved.
P. I. Palmer +10 more
core +2 more sources
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Real Time NMR Analysis of Melamine Formaldehyde Resin Reactions [PDF]
, 2012 This investigation was carried out on behalf of the Momentive Specialty Chemicals Pty Ltd, Mt Maunganui. The aim of the investigation was to develop a method to analyse the formation of melamine formaldehyde resins via an in situ real time NMR experiment
Wang, Yuan
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