Results 201 to 210 of about 449,052 (266)

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu   +4 more
wiley   +1 more source

Enhanced In Vivo Antinociceptive Activity and GC-MS Chemical Profiling of In Vitro-Grown <i>Acmella radicans</i> Plants Elicited with <i>Rhizopus microsporus</i>. [PDF]

open access: yesMolecules
Hernández-Aubert G   +7 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

open access: yesAdvanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi   +11 more
wiley   +1 more source

Effect of Fixative Solutions in Long-Term Bone Preservation. [PDF]

open access: yesBiology (Basel)
Gulimova V   +6 more
europepmc   +1 more source

Preclinical Evaluation of a Microneedle-Delivered Adjuvanted Microparticulate Gonorrhea Vaccine in Non-Human Primates. [PDF]

open access: yesVaccines (Basel)
Ferguson A   +10 more
europepmc   +1 more source

Basic Principles of Skin Biopsy Optimization in Dermatopathology. [PDF]

open access: yesDermatopathology (Basel)
Llamas-Velasco M   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy