Results 41 to 50 of about 15,779,296 (295)

Effects of Intraplantar Morphine in the Mouse Formalin Test

Japanese Journal of Pharmacology, 2000
We studied the effects of intraplantar morphine in the formalin test in mice. Intraplantarly administered morphine (30 - 300 microg) induced analgesic effects at lower doses than intraperitoneally administered morphine. Following the administration of [3H]morphine, the % of radioactivity present in brain was the same by either route.
A, Baamonde, M, Alvarez-Vega, A, Hidalgo, L, Menéndez   +3 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Study on the Effect of Intracuneiformis Nucleus Microinjection of GABAA Receptor Agonist and Antagonist on Antinociceptive Effects of Morphine by Formalin Test in Rat [PDF]

Journal of Kerman University of Medical Sciences, 2005
In the present study, the effects of intracuneiformis nucleus microinjection of gamma-aminobutyric acidA (GABAA) receptor agonist and antagonist on antinociception inducced by morphine were investigated with formalin test in rat. Intracuneiformis nucleus
M Rezvanipour, T Safari, M Abasnejad
doaj  

The effect of Ferula szowitsiana extract on chemical pain in male Wistar rats [PDF]

Archives of Biological Sciences, 2018
Investigations on the use of medicinal plants are appealing to researchers. In Iranian traditional medicine, Ferula szowitsiana is used as an analgesic.
Saghravanian Seyed Javad, Fereidoni Masoud, Asadollahi Ali   +2 more
doaj   +1 more source

Spinal gabapentin is antinociceptive in the rat formalin test

Neuroscience Letters, 1997
Gabapentin is a novel anticonvulsant that may be of value for the relief of clinical pain. To determine whether gabapentin is antinociceptive after spinal administration, the drug was given via an intrathecal catheter in doses from 6 to 200 micrograms/rat 10 min prior to intraplantar formalin.
N, Shimoyama, M, Shimoyama, A M, Davis, C E, Inturrisi, K J, Elliott   +4 more
openaire   +2 more sources

The Effects of Gabapentin on Facial Formalin Test [PDF]

Journal of the Korean Dental Society of Anesthesiology, 2003
Background: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect of this drug was assessed using the formalin test in the rat.
Chul Hong Kim, Seong Wan Baik, Hae Kyu Kim, Jae Young Kwon, Kyoung Hun Kim, Sung Hwan Choi   +5 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

HA- and HI-Test for Myxoviruses with Formalinized Erythrocytes

Nippon Saikingaku Zasshi, 1967
With formalinized erythrocytes (FRC) from chickens, men and guinea-pigs, hemagglutination and hemagglutination-inhibition test for myxoviruses with Salk pattern method were studied and the results obtained are as follows.1) Spontaneous agglutination of FRC was prevented with 0.05 per cent bovine serum albumin in the suspending medium.2) There was no or
Y, Yamaji, M, Takahashi, Y, Miyanaga, Y, Todome, Y, Kimura   +4 more
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Methyl Red Based Test Strip for Identification of Formalin Compounds in Fish Samples

Berkala Sainstek
Methyl red based test strips were introduced a simple method for formalin identification. The test strip was designed based on the feasibility of the formalin oxidation reaction using hydrogen peroxide in an alkaline medium and using the methyl red ...
Lina Sun Haji, Choirun Nisa Anida, Caleysda Aprilianti, Himayah Izmi Fauziyyah, Diah Ayu Pitaloka, Zulfikar Zulfikar   +5 more
doaj   +1 more source