Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Pengaruh Formalin Peroral Dosis Bertingkat Selama 12 Minggu Terhadap Gambaran Histopatologis Hepar Tikus Wistar [PDF]
, 2012 Background: Formalin is a liquid form of formaldehyde that had functions ascadaver preservative. Although prohibited with statutes, there was groceries andfoods contained formalin.
Margawati, A. (Ani) +2 more
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Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
, 2007 Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source
Contribution of the intra-hippocampal orexin system in the regulation of restraint stress response to pain-related behaviors in the formalin test [PDF]
, 2023 Mehdi Sadeghi +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Study on the Effect of Intracuneiformis Nucleus Microinjection of GABAA Receptor Agonist and Antagonist on Antinociceptive Effects of Morphine by Formalin Test in Rat [PDF]
Journal of Kerman University of Medical Sciences, 2005 In the present study, the effects of intracuneiformis nucleus microinjection of gamma-aminobutyric acidA (GABAA) receptor agonist and antagonist on antinociception inducced by morphine were investigated with formalin test in rat. Intracuneiformis nucleus
M Rezvanipour, T Safari, M Abasnejad
doaj
The effect of Ferula szowitsiana extract on chemical pain in male Wistar rats [PDF]
Archives of Biological Sciences, 2018 Investigations on the use of medicinal plants are appealing to researchers. In Iranian traditional medicine, Ferula szowitsiana is used as an analgesic.
Saghravanian Seyed Javad +2 more
doaj +1 more source
DETEKSI KANDUNGAN FORMALIN PADA KEUMAMAH DI PASAR TRADISIONAL KOTA BANDA ACEH [PDF]
, 2015 Tujuan penelitian ini adalah untuk mendeteksi kandungan formalin pada keumamah yang dijual di pasar tradisional Kota Banda Aceh. Sampel penelitian dipilih secara purposive pada lima pasar tradisional Kota Banda Aceh yaitu pasar LY, UK, ST, PY, dan pasar ...
Cici Nabila Putri
core
The Effects of Gabapentin on Facial Formalin Test [PDF]
Journal of the Korean Dental Society of Anesthesiology, 2003 Background: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect of this drug was assessed using the formalin test in the rat.
Chul Hong Kim +5 more
openaire +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source