Results 41 to 50 of about 7,280,633 (297)
Effects of Intraplantar Morphine in the Mouse Formalin Test
Japanese Journal of Pharmacology, 2000 We studied the effects of intraplantar morphine in the formalin test in mice. Intraplantarly administered morphine (30 - 300 microg) induced analgesic effects at lower doses than intraperitoneally administered morphine. Following the administration of [3H]morphine, the % of radioactivity present in brain was the same by either route.
Baamonde, Ana +3 more
openaire +2 more sources
Journal of Pharmacological Sciences, 2008 We evaluated the effects of zonisamide on inflammatory and neuropathic pain using the mouse formalin test and streptozotocin (STZ)-induced diabetic mice with a reduced withdrawal threshold to mechanical stimuli, respectively.
Mitsuo Tanabe +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A Quantitative Test between Formalin Fresh and Boiled Fish at the Fish Market in Tulungagung
Jurnal Keperawatan, 2020 Introduction: Fish is one of the sources of animal protein that many people look for because it is readily available and affordable. Nowadays, found in many traditional markets of traders, fish managers use formalin to preserve their wares.
Lilis Setyowati +2 more
doaj +1 more source
, 2010 This study investigated the mechanisms involved in the antinociceptive action induced by levo-tetrahydropalmatine (L-THP) in the formalin test by combined comparative and chemical proteomics. Rats were pretreated with L-THP by the oral route (40 mg/kg) 1
Jiang, Chunlei +14 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Relationship Between Left and Right PAG in Rat in Unilateral Pain in the Formalin Test [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017 Background: Pain is a protective process in the body. There are different pathways for pain control in the central nervous system. Descending pain control system is one of pathways.
Olya Moshiri +2 more
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Long-term ovariectomy changes formalin-induced licking in female rats: the role of estrogens
Reproductive Biology and Endocrinology, 2003 Gonadal hormones have been shown to exert modulatory effects on nociception and analgesia. To investigate the role of gonadal hormones in the response by female rats to both phasic and persistent nociceptive stimulation, we evaluated the effects of long ...
Massafra Cosimo +3 more
doaj +1 more source