Results 1 to 10 of about 24,005 (140)

Antinociceptive Effects of Free and β-Cyclodextrin-Associated α-Phellandrene in CFA-Induced Inflammatory Pain [PDF]

Biomedicines
Background/Objectives: α-Phellandrene (α-PHEL) is a monoterpene found in essential oils and is known for its antinociceptive and anti-inflammatory properties.
Ana Rita de Sousa França, Wilmara de Carvalho Santos, Matheus Rocha de Seixas Nogueira, Elza Mayara Antunes de Macedo Andrade, Antonio Carlos dos Reis Filho, Eduardo Lima Feitosa, Sidney Gonçalo de Lima, Francisco das Chagas Alves Lima, Francisco Ivan da Silva, Damião Pergentino de Sousa, Antonia Laíres da Silva Santos, Francisco de Assis Oliveira, Fernanda Regina de Castro Almeida   +12 more
doaj   +2 more sources

Sex Differences in the Effects of L-Menthol on Nociception in the Hot Plate Test and Acetic Acid Writhing Test in BALB/c Mice [PDF]

Iranian Journal of Medical Sciences
Background: Sex differences can influence the effects of opioid and non-opioid analgesics. This study evaluated the antinociceptive effects of L-menthol in male and female mice.Methods: This experimental study was conducted in 2024 at Shiraz University ...
Maryam Ahmadnasr, Batool-Faegheh Baha’addiny Baigy Zarandi, Mohammad Reza Panjehshahin, Azar Purkhosrow, Shayan Bahadoori   +4 more
doaj   +2 more sources

The antinociceptive effects of folic acid using formalin and acetic acid tests in male mice [PDF]

Journal of Shahrekord University of Medical Sciences, 2021
Background and aims: Antidepressant agents such as imipramine are clinically used to control and treat different types of pain, especially neuropathic pain. Studies have shown the antidepressant-like activity of folic acid (FA).
Morteza Hajiallilo, Saeid Abbasi-Maleki
doaj   +1 more source

Accelerated Solvent Extractions (ASE) of Mitragyna speciosa Korth. (Kratom) Leaves: Evaluation of Its Cytotoxicity and Antinociceptive Activity

Molecules, 2021
Mitragyna speciosa Korth (kratom) is known for its psychoactive and analgesic properties. Mitragynine is the primary constituent present in kratom leaves.
Yong Sean Goh, Thiruventhan Karunakaran, Vikneswaran Murugaiyah, Rameshkumar Santhanam, Mohamad Hafizi Abu Bakar, Surash Ramanathan   +5 more
doaj   +1 more source

Antinociceptive effect of plant-based natural products in chemotherapy-induced peripheral neuropathies: A systematic review

Frontiers in Pharmacology, 2022
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent and difficult-to-treat symptoms in cancer patients. For this reason, the explore for unused helpful choices able of filling these impediments is essential.
Wagner Barbosa Da Rocha Santos, Juliana Oliveira Guimarães, Lícia Tairiny Santos Pina, Mairim Russo Serafini, Mairim Russo Serafini, Adriana Gibara Guimarães   +5 more
doaj   +1 more source

Tualang Honey: A Decade of Neurological Research

Molecules, 2021
Tualang honey has been shown to protect against neurodegeneration, leading to improved memory/learning as well as mood. In addition, studies have also demonstrated its anti-inflammatory and antioxidant properties.
Khairunnuur Fairuz Azman, Che Badariah Abd Aziz, Rahimah Zakaria, Asma Hayati Ahmad, Nazlahshaniza Shafin, Che Aishah Nazariah Ismail   +5 more
doaj   +1 more source

Synthesis and Modification of Morphine and Codeine, Leading to Diverse Libraries with Improved Pain Relief Properties

Pharmaceutics, 2023
Morphine and codeine, two of the most common opioids, are widely used in the clinic for different types of pain. Morphine is one of the most potent agonists for the μ-opioid receptor, leading to the strongest analgesic effect.
Mona Kamelan Zargar Zarin, Wim Dehaen, Peyman Salehi, Amir Ata Bahmani Asl   +3 more
doaj   +1 more source

Experimental evaluation of anti-inflammatory, antinociceptive and antipyretic activities of clove oil in mice [PDF]

Libyan Journal of Medicine, 2015
Background: Clove oil of Eugenia caryophyllata (Myrtaceae) is a light yellowish fluid obtained from dried flower buds. Clove oil is used traditionally to relieve toothache.
Yousef A. Taher, Awatef M. Samud, Fathy E. El-Taher, Ghazala ben-Hussin, Jamal S. Elmezogi, Badryia F. Al-Mehdawi, Hanan A. Salem   +6 more
doaj   +1 more source

Antinociceptive Effect of a Sacro-Coccygeal Epidural of Morphine and Lidocaine in Cats Undergoing Ovariohysterectomy

Veterinary Sciences, 2022
Background: A commonly described analgesic protocol for ovariohysterectomy (OHE) combines systemic opioids, sedatives, and non-steroidal anti-inflammatory drugs.
Amândio Dourado, Anabela Gomes, Paulo Teixeira, Luís Lobo, Jorge T. Azevedo, Isabel R. Dias, Rui Pinelas   +6 more
doaj   +1 more source

Evaluation of Biocompatibility, Anti-Inflammatory, and Antinociceptive Activities of Pequi Oil-Based Nanoemulsions in In Vitro and In Vivo Models

Nanomaterials, 2022
Pequi oil (Caryocar brasiliense) contains bioactive compounds capable of modulating the inflammatory process; however, its hydrophobic characteristic limits its therapeutic use.
Andréia C. Pinheiro, Alicia S. Ombredane, Willie O. Pinheiro, Laise R. Andrade, Vitória R. P. Silva, Gisela J. Felice, Débora S. Alves, Aryanne F. Albernaz, Ariane P. Silveira, Milena C. F. Lima, Valdir F. Veiga-Junior, Thamis F. S. Gomes, Emanuel A. M. Damasceno, Fabiane H. Veiga-Souza, Paulo E. N. Souza, Sônia N. Báo, Eliza C. B. Duarte, Marcella L. B. Carneiro, Ricardo B. Azevedo, Mani I. Funez, Graziella A. Joanitti   +20 more
doaj   +1 more source