Results 51 to 60 of about 1,457 (209)

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

Durch anomere Amide ermöglichte divergente Synthese unsymmetrischer Harnstoffe, Carbamate, Thioester und Amide aus Aldehyden

Angewandte Chemie, EarlyView.
Eine divergente Aldehyd‐Funktionalisierungssequenz, ermöglicht durch ein anomeres Amid, erlaubt den Ein‐Topf‐Zugang zu unsymmetrischen Harnstoffen, Carbamaten, Thiocarbamaten, Thioestern und Amiden. Entscheidend für diese Transformation ist die Bildung von N‐Boc‐Hydroxamat‐Intermediaten, die als Plattformen für eine orthogonale Aktivierung über Lossen ...
Jasper L. Tyler, Meiyi Zeng, Julius Wiener, Marie‐Christin Leusmann, Colin Stein, Constantin G. Daniliuc, Frank Glorius   +6 more
wiley   +1 more source

Multifaceted catalytic hydrogenation of amides via diverse activation of a sterically confined bipyridine–ruthenium framework

Scientific Reports, 2017
Amides are ubiquitous and abundant in nature and our society, but are very stable and reluctant to salt-free, catalytic chemical transformations. Through the activation of a “sterically confined bipyridine–ruthenium (Ru) framework (molecularly well ...
Takashi Miura, Masayuki Naruto, Katsuaki Toda, Taiki Shimomura, Susumu Saito   +4 more
doaj   +1 more source

Anomeric Amide Enabled Divergent Synthesis of Unsymmetrical Ureas, Carbamates, Thioesters, and Amides From Aldehydes

Angewandte Chemie International Edition, EarlyView.
An anomeric amide‐enabled divergent aldehyde functionalization sequence provides one‐pot access to unsymmetrical ureas, carbamates, thiocarbamates, thioesters, and amides. Key to this transformation is the formation of N‐Boc‐hydroxamate intermediates, which serve as platforms for orthogonal activation via Lossen‐type rearrangements, single‐electron ...
Jasper L. Tyler, Meiyi Zeng, Julius Wiener, Marie‐Christin Leusmann, Colin Stein, Constantin G. Daniliuc, Frank Glorius   +6 more
wiley   +1 more source

Phosphorylation of Milkweed Fibers With a Phosphate Ester: Effect on Fiber Properties and Optimization of Reaction Conditions

Journal of Applied Polymer Science, EarlyView.
The phosphorylation of milkweed fibers using the phosphate ester/urea system was optimized. The impact of reaction temperature, duration, and phosphate ester ratio on the efficiency of phosphorylation was investigated using the design of experiments approach.
Ahmed Azrrar, François Brouillette, Zahahe Oulame Mouandhoime, Saïd Elkoun, Mathieu Robert   +4 more
wiley   +1 more source

One-pot two-step reduction of CO2 with amines and NaBH4 to N-substituted compounds at atmospheric pressure

Journal of CO2 Utilization
In this paper, the reductive N-formylation, methylation and cyclization of amines with carbon dioxide (CO2) using sodium borohydride (NaBH4) at atmospheric pressure, via a one-pot two-step procedure, is presented. Formato borohydride (NaBHn(OCHO)4-n), in
Junhong Wang, Bianling Wang, Xuehong Wei, Zhiqiang Guo   +3 more
doaj   +1 more source

Molecular methods for differentiating Phragmites australis subspecies and identification of hybrid stands in the Upper Midwestern United States

Applications in Plant Sciences, EarlyView.
Abstract Premise In North America, Phragmites australis (common reed) has drawn a great deal of research attention. Non‐native P. australis subsp. australis is a noxious weed that has locally displaced native P. australis subsp. americanus in some areas.
Nicholas P. Tippery, Daniel J. Larkin, Julia Bohnen, Douglas L. Wendell, Neil O. Anderson, Susan M. Galatowitsch, Marie Abbey, Alan G. Smith, Andrzej K. Noyszewski   +8 more
wiley   +1 more source

Engineering Biochar‐Derived Functional Materials for High‐Performance Supercapacitors: Design Principles, Mechanisms, and Scalable Strategies

Carbon Energy, EarlyView.
ABSTRACT Biochar has emerged as a useful and adaptable source of carbon for supercapacitor electrodes. Its value comes from the way biomass chemistry, thermal conversion, and activation conditions shape the resulting pore network, surface groups, and degree of carbon ordering.
Soumen Mandal, Avinash C. Mendhe, Mayna Roy, Neha S. Barse, Taejoon Park, Han‐Seung Lee, Haigun Lee   +6 more
wiley   +1 more source

In situ Generation of Fluoride Catalysts for CO2‐to‐Formic Acid Conversion With Silicon Reducing Agent

Chemistry – A European Journal, EarlyView.
Reductive conversion of CO2 to formic acid with waste silicon reducing agent catalyzed by in situ generation of active fluoride species from a tertiary amine, protonic acid, and simple inorganic fluoride salt, such as KF and NaF. ABSTRACT The activation and catalytic reduction of carbon dioxide (CO2) using silicon‐based reducing agents is an important ...
S. M. A. Hakim Siddiki, Yusuke Tanimura, Mariko Honda, Shingo Hasegawa, Kazuo Namba, Yuichi Manaka, Ken Motokura   +6 more
wiley   +1 more source

Impact of Organo‐Functionalization on the Light‐Driven Hydrogen Evolution Reactivity of Molecular Molybdenum Sulfides

Chemistry – A European Journal, EarlyView.
Organo‐functionalized molecular molybdenum sulfides were synthesized using bidentate N‐donor ligands and investigated as light‐driven homogeneous hydrogen evolution reaction (HER) catalysts. Trends observed in the HER activity of these catalysts were elucidated by combining photophysical, electrochemical and computational studies.
Moritz Jahn, Luis Kammerer, Luca Schleicher, Amelie Meyer, Mariet Sibi Puthanagady, Alexander K. Mengele, Sven Rau, Stephan Kupfer, Benjamin Dietzek‐Ivanšić, Carsten Streb   +9 more
wiley   +1 more source