Results 71 to 80 of about 1,457 (209)

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

Vocal Outcomes After Cell‐Based Outer Vocal Fold Implant in Porcine Bilateral Vocal Fold Resection

The Laryngoscope, EarlyView.
Cell‐based outer vocal fold replacement (COVR) was evaluated in a porcine model of bilateral vocal fold injury using longitudinal acoustic analysis and histologic assessment. COVR implantation resulted in recovery of the nonperiodic acoustic parameter Q50 to preoperative levels by 6 months, with implanted human adipose‐derived stem cells detected in 7 ...
Keer Zhang, Georgia Crane, Mateo Ruiz Alvarez, Alexandra Klomhaus, Yazeed Alhiyari, Bhavani Gowda, Michael Döllinger, Jennifer Long   +7 more
wiley   +1 more source

Screening and Profiling of Antioxidant Activity in Mud Crab (Scylla Serrata) from Banyuasin Waters

Ilmu Kelautan
Mangrove crab (Scylla serrata) as one of the crustacean species, has a variety of bioactive compounds that can be utilized in the field of pharmacology. Antioxidant compounds act as therapeutic agents against degenerative diseases.
Rozirwan Rozirwan, Ning Intan Lestari, Yoga Winarta, Isnaini Isnaini, Wike Ayu Eka Putri, Muhammad Hendri, Tengku Zia Ulqodry, Fauziyah Fauziyah, Melki Melki, Redho Yoga Nugroho, Che Abd Rahim Mohamed   +10 more
doaj   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

A robust and reusable heteroatom-doped nanocatalyst for the synthesis of enol carbamates via oxidative coupling of formamides: molecular docking as potential leukocyte elastase inhibitors

Results in Chemistry
The development of sustainable and efficient strategies for carbamate synthesis remains a key challenge in synthetic chemistry. Herein, we report a magnetic, MOF-derived copper catalyst (CoFe₂O₄@CNSCu) for the oxidative synthesis of enol carbamates under
Firouz Matloubi Moghaddam, Hassan Fazli, Pantea Montazeri   +2 more
doaj   +1 more source

Polyvinylidene Fluoride: Reaction Engineering and Applications

Macromolecular Reaction Engineering, EarlyView.
An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian, Giuseppe Storti, Mattia Sponchioni   +2 more
wiley   +1 more source

Polylactide/Graphene Nanoplatelet Composites for Advanced Functional Applications

Polymer Composites, EarlyView.
Polylactide/Graphene nanoplatelet composites for advanced functional applications. ABSTRACT This study investigates the structure–property relationships of polylactide (PLA) nanocomposites containing graphene nanoplatelets (GNP) and trimellitic anhydride‐modified GNPs (TMA‐GNP).
Shivanthi Dharmarathna, Haritha Haridas, Hadi Hosseini, Mehdi Babazadeh, Carlos E. Saavedra, Marianna Kontopoulou   +5 more
wiley   +1 more source

Decoupling Formulation and Processing Effects in Thermoplastic Starch Through a Data‐Driven Structure–Property Framework

Polymer Engineering &Science, EarlyView.
Processing‐property relationships in thermoplastic starch (TPS): plasticizer type, starch source and melt‐processing temperature establish a hierarchy of effects that governs process‐induced changes and the resulting TPS properties. ABSTRACT Thermoplastic starch (TPS) is a melt‐processable biopolymer whose properties depend strongly on formulation and ...
Cristina Pavón, Nerea Martínez, Alexandra Llidó Barragán, Juan López‐Martínez   +3 more
wiley   +1 more source