Results 31 to 40 of about 872,972 (311)

ANTIBODY FORMATION [PDF]

open access: yesThe Journal of Experimental Medicine, 1963
Injection of a sufficient dose of bacteriophage ϕX 174 into guinea pigs results in the formation of rapidly sedimenting antibody molecules (19S), and later, slowly sedimenting molecules (7S). Above a threshold dose of antigen, the relative rate of 19S formation is maximal and dose-independent; below this dose, slower relative rates are obtained.
Martin S Finkelstein, Jonathan W Uhr
openaire   +1 more source

Evaluation of a New, Community‐Based Screening Program to Detect Hearing Loss in Adult Childhood Cancer Survivors in Switzerland: Findings From the HEAR Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCS) have an increased risk of long‐term health complications, including treatment‐related hearing loss. Although early detection is important, many adult survivors do not attend hearing screenings in clinical centers because visits can be logistically or emotionally burdensome.
Philippa Jörger   +9 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Towards a micropolitics of formats

open access: yesRevue d'anthropologie des connaissances, 2019
This article crosses perspectives from science studies, French information and communication sciences and cultural studies. We analyze the Content ID apparatus published by the company and video publishing site YouTube, which identifies the music tracks ...
Guillaume Heuguet
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Les formats des écrits numériques. Une analyse topologique de la mise à l'écran

open access: yesOcula
Digital writings, like writings in general, are presented visually to the reader through different forms depending on the discourse of circulation and the distribution devices.
Rossana De Angelis
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Microstructure-Properties of Dynamically Vulcanized Mengkuang Leaf Fibre/Ethylene Vinyl Acetate/Natural Rubber Thermoplastic Elastomer Composites

open access: yesBioResources, 2022
Thermoplastic elastomer composites based on ethylene vinyl acetate (EVA), natural rubber (NR), and Mengkuang leaf fibre were prepared using the sulfur and peroxide vulcanization systems.
Faiezah Hashim   +3 more
doaj   +2 more sources

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