Results 151 to 160 of about 14,011,216 (334)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Studies on In Vivo Formation of Nitroso Compounds (I)

open access: diamond, 1975
Motoo Harada   +4 more
openalex   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Presolar Heritage of 50Ti and 26Al Heterogeneity in the Protoplanetary Disk

open access: yesThe Astrophysical Journal
Nucleosynthetic isotope anomalies have been documented within the solar protoplanetary disk for several isotopes, including ^48 Ca, ^50 Ti, ^54 Cr, ^94 Mo, and ^96 Zr.
Kirsten K. Larsen   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Uranium-lead age of monazite from granite of the gaysin complex (Ros-Tikits megablock of the Ukrainian shield

open access: yesМінеральні ресурси України, 2017
Haysin complex includes granitoids that form a continuous series of rocks: diorite – quartz diorite – granodiorite – amphibole–biotite granite – biotite granite – pink applet-pegmotoid granite.
L. M. Stepanyuk   +4 more
doaj  

Understanding health needs of professional truck drivers to inform health services: a pre-implementation qualitative study in a Canadian Province

open access: yesBMC Public Health
Objectives Long-haul truck drivers experience multiple challenges, including increased health risks. A large percentage of professional truck drivers (PTDs) suffer from numerous chronic physical health conditions such as obesity, hypertension, diabetes ...
Jalila Jbilou   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy