Results 281 to 290 of about 14,011,216 (334)

Gap Formation and Fixation Strength After Unicortical Quadriceps Tendon Repair with All-Suture Anchors. [PDF]

Orthop J Sports Med
Werner BC, Tejada MD, Wittstein JR, Frank RM, Evans MK, Khoury AN, Smith BL.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Integrating 3D structural modelling and seismic interpretation to optimize hydrocarbon development in the Early Miocene Nukhul Formation, October Oil Field, Gulf of Suez, Egypt. [PDF]

Sci Rep
Khattab MA, Radwan AE, El-Anbaawy MI, El-Tehiwy AA.   +3 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Acetic acid induces proteasome storage granule formation and inhibits proteasomal proteolysis: Comparison with other induction conditions. [PDF]

J Biol Chem
Imajo M, Tanaka S, Anh Nguyet VT, Hayashi M, Matsuura A, Izawa S.   +5 more
europepmc   +1 more source

MARCH7 E3 ubiquitin ligase is highly expressed in developing spermatids of rats and its possible involvement in head and tail formation

, 2013
博強 趙
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Study on the Source Contributions of Gas Reservoirs in the Dongfang and Ledong Areas of the Yinggehai Basin. [PDF]

ACS Omega
Pei J, Guo X, Xue H, Wu Y, Dong Z, Yan J.   +5 more
europepmc   +1 more source