Results 231 to 240 of about 9,333,414 (344)

Conserved 3D genome reorganization during DNA repair. [PDF]

Life Sci Alliance
Kaya VO, Adebali O, Naegeli H, Yancoskie MN.   +3 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Formation of high-aspect-ratio nanocavity in LiF crystal using a femtosecond X-ray free-electron laser pulse. [PDF]

Nat Commun
Makarov SS, Zhakhovsky VV, Grigoryev SY, Chuprov P, Pikuz TA, Inogamov NA, Khokhlov VA, Petrov YV, Perov EA, Shepelev V, Shobu T, Tominaga A, Rapp L, Juodkazis S, Makita M, Nakatsutsumi M, Preston TR, Appel K, Konopkova Z, Cerantola V, Brambrink E, Schwinkendorf JP, Mohacsi I, Vozda V, Hajkova V, Burian T, Chalupsky J, Juha L, Ozaki N, Kodama R, Zastrau U, Rode AV, Pikuz SA.   +32 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Dynamic genome-wide mapping reveals how chromatin context shapes OGG1-mediated repair and related mutagenesis in human cells. [PDF]

Nucleic Acids Res
Li J, Li L, Tan Y, Yin M, Li Y, Yin D, An J, Zhuang G, Qian M, Hu J.   +9 more
europepmc   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Comprehensive Evaluation of the Genotoxic Potential of Food Additive Titanium Dioxide in Human Intestinal Cell Systems. [PDF]

Int J Mol Sci
Nam HN, Jeong SM, Kim SB, Choi SJ.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Exploring cell death mechanisms in liver transplantation: implications for graft survival. [PDF]

Front Immunol
Hirao H, Watanabe T, Uchida Y, Hatano E.
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source