Results 41 to 50 of about 1,178,980 (262)

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

Experimental study of petrophysical properties of a tight formation by considering the clay minerals and flow sensitivities

open access: yesEarth Sciences Research Journal, 2016
Quantitative X-ray diffraction analysis of rock, X-ray diffraction analysis of clay minerals types and components, Field Emission Scanning Electron Microscope (FESEM) and sensitivity flow experiments methods were used toresearch the effects of clay ...
Guangfen Liu   +4 more
doaj   +1 more source

Geochemical Changes Associated with High-Temperature Heat Storage at Intermediate Depth: Thermodynamic Equilibrium Models for the DeepStor Site in the Upper Rhine Graben, Germany

open access: yesEnergies, 2021
The campus of the Karlsruhe Institute of Technology (KIT) contains several waste heat streams. In an effort to reduce greenhouse gas emissions by optimizing thermal power consumption on the campus, researchers at the KIT are proposing a ‘DeepStor ...
Jonathan Banks   +4 more
doaj   +1 more source

Consensus Standards and Recommendations for Developmental and Cognitive Surveillance, Screening, and Evaluation in Sickle Cell Disease: Executive Summary From the National Alliance of Sickle Cell Centers Neurocognitive Workgroup

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz   +12 more
wiley   +1 more source

Rheological properties and damage-control mechanism of oil-based drilling fluid with different types of weighting agents [PDF]

open access: yesRoyal Society Open Science, 2018
The great amount of solid particles contained in a weighting agent is a major cause of the problems in both rheology properties and damage control mechanism of an oil-based drilling fluid (OBM).
Peng Xu   +4 more
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel   +36 more
wiley   +1 more source

Experimental Design for Evaluation of Formation Damage by Microbial Contamination in Water Flooding Processes. A Colombian Study Case.

open access: yesRevista Fuentes El Reventón Energético, 2019
Microbial contamination is well known in the oil and gas industry and it occurs in most processes where water processing systems are involved. Microorganisms are spread everywhere, even in the subsurface, where operations of oil exploration and ...
Manuel Guillermo   +2 more
doaj   +1 more source

Preventing sour gas kicks during workover of natural gas wells from deep carbonate reservoirs with anti‐hydrogen sulfide fuzzy‐ball kill fluid

open access: yesEnergy Science & Engineering, 2022
Workover of natural gas wells in deep carbonate gas reservoirs (DCRs) is facing multiple challenges such as fluid leakage, high temperature, and hydrogen sulfide (H2S) gas kick.
Zhenfeng Yan   +8 more
doaj   +1 more source

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