Results 61 to 70 of about 1,244,178 (311)
Phosphorylation events surrounding the DNA damage response in "Saccharomyces cerevisiae" [PDF]
, 2007 Protein phosphorylation mediated by checkpoint kinases is crucial for the cellular response to DNA damage. The sensor kinases Mec1 and Tel1 initiate the checkpoint signaling cascade by directly activating the checkpoint effector kinase Rad53.
Schleker, Thomas Andreas
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Shock-Induced Damage in Rocks: Application to Impact Cratering [PDF]
, 2006 Shock-induced damage beneath impact craters is studied in this work. Two representative terrestrial rocks, San Marcos granite and Bedford limestone, are chosen as test target.
Ai, Huirong (Anita)
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Revista Fuentes El Reventón Energético, 2019 Microbial contamination is well known in the oil and gas industry and it occurs in most processes where water processing systems are involved. Microorganisms are spread everywhere, even in the subsurface, where operations of oil exploration and ...
Manuel Guillermo +2 more
doaj +1 more source
Energy Science & Engineering, 2022 Workover of natural gas wells in deep carbonate gas reservoirs (DCRs) is facing multiple challenges such as fluid leakage, high temperature, and hydrogen sulfide (H2S) gas kick.
Zhenfeng Yan +8 more
doaj +1 more source
Parameter identification of a mechanical ductile damage using Artificial Neural Networks in sheet metal forming. [PDF]
, 2013 In this paper, we report on the developed and used of finite element methods, have been developed and used for sheet forming simulations since the 1970s, and have immensely contributed to ensure the success of concurrent design in the manufacturing ...
Belhadj, Touhami +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Damage formation on fused silica illuminated with ultraviolet-infrared femtosecond pulse pairs [PDF]
, 2015 Citation: Yu, X., Chang, Z., Corkum, P. B., & Lei, S. (2015). Damage formation on fused silica illuminated with ultraviolet-infrared femtosecond pulse pairs. Proceedings of SPIE.
Corkum, P. B. +10 more
core +1 more source