Results 61 to 70 of about 1,232,407 (262)

A Simple Analytical Approach to Simulate Underbalanced- drilling in Naturally Fractured Reservoirs—The Effect of Short Overbalanced Conditions and Time Effect

Energies, 2010
This paper describes an analytical approach to investigate the nature of short overbalanced conditions and time effects during underbalanced drilling (UBD) in a naturally fractured reservoir.
Knut Inge Andersen, Johan Tronvoll, Siroos Salimi, Ali Ghalambor   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Adsorption and Squeeze Performance of PAMAM-PGLU Inhibitors for Silicate Scale Mitigation Due to Asp Flooding

Platform, a Journal of Engineering
Silica and silicate scale deposition in the production systems resulted in reduced production rates and equipment damages. Chemical scale inhibition using squeeze method is advantageous for petroleum reservoir conditions.
Bee Chea Tan, Ismail Mohd Saaid
doaj   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Research Status and Development Direction of Formation Damage Prediction and Diagnosis Technologies

Applied Sciences
Formation damage remains a key challenge in oil and gas exploration and development, requiring effective prediction and diagnostic technologies to mitigate its impact.
Zhe Sun, Zhangxing Chen
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Analysis of damage mechanisms and controlling factors of fine particle migration in unconsolidated sandstone reservoirs based on reservoir classification

Energy Science & Engineering
Particle migration in oil and gas reservoirs is a common phenomenon in the process of oil and gas development, and is considered to be an important reason for the damage of reservoir permeability and the reduction of oil and gas productivity.
Zhao Wang, Hanjun Yin, Haoxuan Tang, Yawei Hou, Hang Yu, Qiang Liu, Hongming Tang   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Formation damage effects in a horizontal wells completion [PDF]

Acta Montanistica Slovaca, 2001
Horizontal well completions are considered to reduce concerns about formation damage because the extra completion interval length in the pay zone offset production lost from reduced permeability around the wellbore.The control of sand flow from ...
Sidorová Marina
doaj