Results 91 to 100 of about 4,722,147 (302)
Study on the Occurrence of Double Bottom Simulating Reflectors in the Makran Accretionary Zone
A Bottom Simulating Reflector (BSR) is a seismic feature closely related to marine gas hydrate as it is usually regarded as the seismic response of the base of the gas hydrate stability zone in seismic profiles.
Jiangxin Chen +11 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The spatial distribution of tourist attractions plays a critical role in the development of coastal cities. Qingdao, with its coastal geography, rich cultural heritage, and rapid urbanization, serves as a representative case.
Yue Xu +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Tuning the Morphology of ZnO Nanostructures with the Ultrasonic Spray Pyrolysis Process
Nanostructured zinc oxide (ZnO) particles were synthesized by the one step Ultrasonic Spray Pyrolysis (USP) process from nitrate salt solution (Zn(NO3)2·6H2O). Various influential parameters, from Zn(NO3)2·6H2O concentrations (0.01875–
Elif Emil +5 more
doaj +1 more source
Mechanisms of autophagosome formation
The formation of autophagosomes is a pivotal step in autophagy, a lysosomal degradation system that plays a crucial role in maintaining cellular homeostasis. After autophagy induction, phase separation of the autophagy-related (Atg) 1 complex occurs, facilitating the gathering of Atg proteins and organizes the autophagosome formation site, where the ...
Yuko FUJIOKA, Nobuo N. NODA
openaire +2 more sources
Mechanisms of intracellular ice formation
The phenomenon of intracellular freezing in cells was investigated by designing experiments with cultured mouse fibroblasts on a cryomicroscope to critically assess the current hypotheses describing the genesis of intracellular ice: (a) intracellular freezing is a result of critical undercooling; (b) the cytoplasm is nucleated through aqueous pores in ...
Muldrew, K., McGann, L.E.
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A review on rainstorm research in northwest China
The topography and geomorphology of the northwestern region is very complicated. The rainstorms have both advantages and disadvantages. In order to make use of the advantages and avoid the disadvantages, the main progress of the torrential rain in the ...
Yuxia HUANG +4 more
doaj +1 more source

