Results 61 to 70 of about 4,722,147 (302)
ASC filament formation serves as a signal amplification mechanism for inflammasomes [PDF]
, 2016 A hallmark of inflammasome activation is the ASC speck, a micrometre-sized structure formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD), which consists of a pyrin domain (PYD) and a caspase ...
Broz, Petr +4 more
core +1 more source
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Frontiers in Earth ScienceThis study investigates Xunke agates from Ating River alluvial gravels (Northeast, NE China) using optical microscopy, electron probe microanalyzer mapping (EPMA), and laser ablation–inductively coupled plasma–mass spectrometry (LA–ICP–MS) to constrain ...
Peng Zhang +3 more
doaj +1 more source
Shiyou shiyan dizhi, 2021 Different forms of talc have been developed in the first member of Permian Maokou Formation (P2m1) in the Sichuan Basin. As a hydrothermal alteration mineral, its formation mechanism and its influence on the P2m1 reservoir need to be further explored ...
Haixia REN +6 more
doaj +1 more source
, 2014 The $\mathrm{H}_2$ formation on grains is known to be sensitive to dust temperature, which is also known to fluctuate for small grain sizes due to photon absorption.
Bourlot, Jacques Le +2 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
Mechanism of membrane tube formation induced by adhesive nanocomponents
, 2012 We report numerical simulations of membrane tubulation driven by large colloidal particles. Using Monte Carlo simulations we study how the process depends on particle size, concentration and binding strength, and present accurate free energy calculations
A. H. Bahrami +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Ecology and EvolutionThe grass genus Orinus, endemic to the Qinghai‐Tibet Plateau (QTP), has long been taxonomically controversial. Recent integrative studies combining morphological and DNA barcoding proposed revising the genus from six to three species; however, this ...
Ai Liu +7 more
doaj +1 more source
Frontiers in Earth Science, 2021 Characterized by large scale, high frequency, and strong destructiveness, debris flow has become the most noticeable geohazards throughout the world, especially in the mountainous areas of southwestern China.
Yu Li +7 more
doaj +1 more source