Results 131 to 140 of about 5,772,292 (281)

User-centered design and formative evaluation of a gait dashboard for multidimensional walking assessment in multiple sclerosis. [PDF]

open access: yesFront Digit Health
Sedlmayr B   +9 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Improving immunisation coverage in Ethiopia: a formative evaluation in pastoral communities

open access: yes
Stata code files and ready-for-analysis data used in the analysis published in the Final Report to 3ie on the project, "Improving immunisation coverage in Ethiopia: a formative evaluation in pastoral communities" (project code TW 10.1076).
Tolera, Bekana   +3 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Closing the immunisation gap in Ethiopia: a formative evaluation of 'The Fifth Child Project'

open access: yes
Stata code files, ready-for-analysis data and qualitative data used in the analysis published in the Final Report to 3ie on the project, "Closing the immunisation gap in Ethiopia: a formative evaluation of 'The Fifth Child Project'" (project code TW 10 ...
Larson, Heidi   +10 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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