Results 151 to 160 of about 83,452 (253)

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

Journal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan, Shuang Sui, Zhenghua Yang, Kaiwen Zhang, Qiang Hu   +4 more
wiley   +1 more source

Evaluation of Antioxidant-Rich Mexican Oregano (<i>Lippia graveolens</i>) Infusion and Carvacrol: Impact on Metabolic Activity and Cytotoxicity in Breast Cancer Cell Lines. [PDF]

Nutrients
Rojo-Ruvalcaba BE, Maldonado-González M, Cálix-Rodríguez GM, Valdés-Miramontes EH, Gómez-Leyva JF, García-Cobián TA, Sánchez-Hernández PE, Machado-Sulbaran AC, López-Roa RI, Balderas-León I, García-Iglesias T.   +10 more
europepmc   +1 more source

Tempol Protects Against Radiation Injury in the Submandibular Gland Through the β‐Catenin Signaling Pathway

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Radiation damage severely impacts salivary gland function and cell survival, especially in head and neck radiotherapy. Tempol (TPL), a free radical scavenger, has shown protective effects against radiation damage. This research aimed to investigate the protective effects of TPL on radiation‐induced damage in Hs917.T cells and the ...
Jinfeng Wang, Mingjun Xu, Jinghua Zhong, Kui Zhong, Zheng Chen, Chunyu Liu, Chao Liu   +6 more
wiley   +1 more source

Cytotoxicity evaluation of different clear aligner systems on human primary gingival fibroblasts: an in vitro study. [PDF]

Biomater Investig Dent
Das RP, Gangurde PV, Ranjan A, Gaikwad SS, Sawant HR, Karia M.   +5 more
europepmc   +1 more source

Influence of the post‐processing protocol on a biocompatible 3D‐printed resin

Journal of Prosthodontics, EarlyView.
Abstract Purpose This study aimed to evaluate the cytotoxicity of a biocompatible 3D‐printed resin material for occlusal devices after post‐processing with two different high‐intensity UV‐polymerization devices and two rinsing solvents, in the presence of human gingival fibroblasts (HGFs).
Sergio López‐García, Miguel Ramón Pecci‐Lloret, María Pilar Pecci‐Lloret, David García‐Bernal, Ricardo Elías Oñate‐Sánchez   +4 more
wiley   +1 more source

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani. [PDF]

Sci Rep
Das S, Ghosh S, Pal K, Chakraborty M, Khalko S, Islam SM, Rai S, Choudhury A, Sahana N, Mandal S.   +9 more
europepmc   +1 more source

Anti‐Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From Amlodipine‐Induced Gingival Overgrowth

Journal of Periodontal Research, EarlyView.
Resveratrol in repeated doses has been shown to suppress excessive cell proliferation without cytotoxic effects in amlodipine‐induced gingival hyperplasia, while not having a negative effect on mediators involved in tissue homeostasis in healthy cells, and at the same time, it reduces the expression of biomarkers involved in fibrosis processes ...
Bilkan Kara, Nuriye Işıl Saygun, Cansel Köse Özkan, Melis Özgül Slezovic, Muhittin Abdulkadir Serdar, Mualla Pınar Elçi, Alpdoğan Kantarci   +6 more
wiley   +1 more source

Effectiveness of resveratrol as a root canal irrigation solution in inhibiting biofilm and bacterial metabolic activity of Enterococcus faecalis. [PDF]

Lasers Med Sci
Uysal M, Üreyen Kaya B, Sesli Çetin E, Bilir G.   +3 more
europepmc   +1 more source

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

A Dual Cell‐Line Molecular Platform to Assess Sub‐Threshold Biocompatibility: Application to Processed Orthodontic Clears Aligners

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Traditional biocompatibility assessments primarily address cytotoxicity and bulk material properties but often overlook molecular responses that occur below toxicity thresholds. Detecting these subtle effects is crucial for materials intended for prolonged contact with human tissues.
Katia Barbaro, Ettore Candida, Francesca Silvestrini Biavati, Valentina Lanteri, Paola Ghisellini, Cristina Rando, Roberto Eggenhöffner, Alessandro Ugolini   +7 more
wiley   +1 more source