Results 61 to 70 of about 83,452 (253)
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
HYDRAZONES AND FORMAZANS - INVESTIGATION AND TECHNOLOGY
Bulletin of the National Technical University "KhPI". Series: Chemistry, Chemical Technology and Ecology, 2019 Viral infections are a constant human health problem. The growing danger of viral infections necessitates the search for new antiviral drugs that are not toxic to humans. Creating safe and effective antiviral drugs is difficult because viruses use host cells for replication.
Distanov, Vitaly Balamirovich +4 more
openaire +3 more sources
Advanced Science, EarlyView.This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng +7 more
wiley +1 more source
The MTT-formazan assay: Complementary technical approaches and in vivo validation in Drosophila larvae [PDF]
, 2018 The MTT assay was the first widely accepted method to assess cytotoxicity and cell viability. However, there is controversy on whether this indicator is a useful tool.
Ganfornina, M. D. +11 more
core +1 more source
Advanced Science, EarlyView.We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo +7 more
wiley +1 more source
X-ray diffraction investigation of 1-phenyl-3-isopropyl-5-(benzothiazol-2- yl)formazan [PDF]
, 2008 The crystal structure of 1-phenyl-3-isopropyl-5-(benzothiazol-2-yl)formazan is investigated using X-ray diffraction. The compound crystallizes in the form of two crystallographically independent molecules (A and B) in identical conformations that are ...
Slepukhin, P. A. +5 more
core
Advanced Science, EarlyView.ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning +7 more
wiley +1 more source
Novel nitro-substituted formazan derivatives: selective ratiometric and colorimetric chemosensors for fluoride anion sensing detectable by the naked eye [PDF]
, 2020 Two novel formazan derivatives,FNBandFDNB, were synthesized from the corresponding phenylhydrazones and characterized by various spectroscopic methods.
Turkoglu G.
core +1 more source
Advanced Science, EarlyView.Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen +17 more
wiley +1 more source
Formazan ring method: a simple test for screening of glucoce-6-phosphate dehydrogenase (G-6-PD) deficiency in the neonates [PDF]
, 1996 Glucose-6-phosphate dehydrogenase deficiency, is an x-linked inherited disease which is responsible for episodic hemolytic anemia. The incidence correlates with the malarial epidemic in many area like Mediterranean, Africa and Asia including South East ...
Perpustakaan UGM, i-lib
core +3 more sources