Results 191 to 200 of about 1,821 (267)

Advancements in boron difluoride formazanate dyes for biological imaging. [PDF]

Curr Opin Chem Biol
Yang S, Lu K, Xiao H.
europepmc   +1 more source

Kaempferol Improves Alzheimer's Disease by Inhibiting Neuronal Ferroptosis via Activating GPX4/AKR1C3 Signaling Pathway

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li, Manying Yang, Jiale Tao, Yonghong Zhao, Na Zhao, Shiguo Sun   +5 more
wiley   +1 more source

Emulsifier-modified sunflower oil-sunflower wax oleogel as growth modulator of probiotics. [PDF]

BBA Adv
Bharti D, Kulanthaivel S, Mishra P, Jain N, Pal K, Banerjee I.   +5 more
europepmc   +1 more source

Protective effect of snail secretion filtrate in an in vitro model of mastitis

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Bovine mastitis is inflammation of the mammary gland mainly caused by bacterial infections, with relevant economic costs and implications related to antibiotic resistance. In light of the increasing demand for sustainable therapies, this study evaluated the anti‐inflammatory and antioxidant effects of snail secretion filtrate (SSF ...
Gianluca Antonio Franco, Ylenia Marino, Rosalia Crupi, Davide di Paola, Salvatore Cuzzocrea, Enrico Gugliandolo   +5 more
wiley   +1 more source

Benzimidazole-Coordinated Copper(II) Complexes as Effectual Chemotherapeutics against Malignancy. [PDF]

ACS Omega
Saha A, Debnath A, Chettri M, Mahato RK, Das D, Sarkar D, Chaurasia R, Bhattacharyya S, Mukherjee M, Biswas B.   +9 more
europepmc   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

Molecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes, Travis J. Chiarelli, Doaa N. Abdallah, Grayson Way, Huiping Zhou, Jason A. Carlyon, Daniel P. Miller   +6 more
wiley   +1 more source

Crizotinib- or Ceritinib-Conjugated Platinum(IV) Prodrugs As Potent Multiaction Agents Inducing Antiproliferative Effects in 2D and 3D Cancer Cell Models. [PDF]

J Med Chem
Sharkawy S, Acharya S, Kostrhunová H, Maji M, Marková L, Novohradský V, Gibson D, Brabec V.   +7 more
europepmc   +1 more source

Engineering Electrospun PCL/PEO Membranes With ECM‐Like Architecture and Tunable Hydrophilicity as Functional Wound Dressings

Journal of Applied Polymer Science, Volume 143, Issue 17, May 5, 2026.
Schematic illustration of the production of PCL/PEO electrospun membranes and their morphological, physical, and biological characterization. ABSTRACT Skin injuries resulting from trauma, burns, or chronic conditions such as diabetes often require advanced medical interventions, as conventional dressings provide only passive protection with limited ...
Ronaldo Bianchini da Silveira, Maria Fernanda Pedro Ebs, Renata Bochanoski, Mateus de Assunção Hofmann, Oscar Rubem Klegues Montedo, Thauan Gomes, Sabrina Arcaro   +6 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, Volume 16, Issue 5, Page 906-920, May 2026.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Copper Overload Affects α‐Synuclein Clearance Mechanisms in a Parkinson's Disease In Vitro Model

Advanced Biology, Volume 10, Issue 5, May 2026.
This study reveals that copper overload disrupts neuronal protein clearance, leading to the accumulation of α‐synuclein and its phosphorylated form (p‐S129). By blocking autophagy and impairing the ubiquitin–proteasome system, copper promotes toxic aggregation in dopaminergic cells.
Debora Musarò, Marina Damato, Chiara Coppola, Marco Greco, Michele Maffia   +4 more
wiley   +1 more source