Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Computational study of the CO 2 hydrogenation to formic acid catalyzed by a P,P-bidentate copper(I) complex. [PDF]
Santos SA +4 more
europepmc +1 more source
Ultrasmall CoP Nanoparticles as Efficient Cocatalysts for Photocatalytic Formic Acid Dehydrogenation
Shuang Cao +9 more
semanticscholar +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Corrosion Behavior and Degradation Mechanism of High-Alloy Bainitic Gray Cast Iron Cylinder Liners for Methanol Engines in Formic Acid-NaCl Media. [PDF]
Yang SB +7 more
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Formic acid released by intratumoral <i>Bacteroides thetaiotaomicron</i> facilitates combinational therapy of Apatinib and aPD-1 in hepatocellular carcinoma. [PDF]
Lu J +11 more
europepmc +1 more source
Electrochemical conversion of CO2 to formic acid utilizing Sustainion™ membranes
Hong-Zhou Yang +3 more
semanticscholar +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source

