Results 141 to 150 of about 236,293 (298)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Formic acid regeneration by electromembrane processes

, 2006
International audienceWaters containing low amounts of sodium formate and sodium hydroxide were processed in order to regenerate formic acid. The treatment was performed in three steps: wastewaters neutralization, sodium formate concentration by ...
Durand, Gerard, Laborie, Stephanie, Jaime Ferrer, J.Salvador, Rakib, Mohammed   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

An investigation on the Effect of some Additives on Aerobic Stability, Chemical Composition and Microbes of Corn Silage

پژوهشهای علوم دامی ایران, 2013
This experiment was conducted to determine the effects of propionic acid, formic acid, molasses and molasses plus urea on chemical composition, microbial population, ruminal degradability of dry matter (DM) and crude protein (CP), and aerobic stability ...
T. Ghoorchi, F. Ghanbari, T. Ebrahimi
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineering a Formic Acid Reductase

ACS Catalysis
The formate bioeconomy envisions production of formic acid from CO2 via (electro-)chemical conversion, followed by conversion to the product by engineered microbes or cell-free systems. One prominent way of expanding formate valorization is its reduction to formaldehyde, making highly efficient assimilation cascades accessible.
Philipp Wichmann, Amelia Cox-Fermandois, Andreas M. Küffner, Uwe Linne, Tobias J. Erb, Maren Nattermann   +5 more
openaire   +2 more sources

Synergistic chemo-enzymatic formic acid disproportionation and biomolecular condensates for efficient amino acid production

Journal of CO2 Utilization
Formic acid, which can be sustainably produced from CO₂ electroreduction, serves as a renewable liquid C₁ carrier for carbon recycling. However, its biological assimilation is fundamentally constrained by unfavorable thermodynamics and limited metabolic ...
Aocong Guan, Yin Gao, Minhui Wang, Jinglei Nie, Jianming Liu, An-Ping Zeng   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Kinetics of Formic Acid Decomposition in Subcritical and Supercritical Water - A Raman Spectroscopic Study

, 2019
The decomposition of formic acid is studied in a continuous sub- or supercritical water reactor at temperatures between 300 and 430°C, a pressure of 25 MPa, residence times between 4 and 65 s, and a feedstock concentration of 3.6 wt%.
Brian, Pinkard, John, Kramlich, Elizabeth, Rasmussen, Per G., Reinhall, Igor V., Novosselov, David, Gorman   +5 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source