Results 111 to 120 of about 3,574,206 (236)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Overlap fluctuations in glass-forming liquids

, 2013
We analyse numerically thermal fluctuations of the static overlap between equilibrium configurations in a glass-forming liquid approaching the glass transition.
Berthier, Ludovic
core   +4 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Decision of pedagogical tasks as mean of forming of pedagogical position of students of higher education physical establishments [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
In the article one of terms of forming of pedagogical position for the students of higher education physical establishments - decision of educational-pedagogical situations (EPS) is examined. Monitoring of progress from pedagogical disciplines confronted
Stepanchenko N.I., Matvijchuk T.F.
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A ROBUST OPTIMISATION-EFFICIENCY-DECISION SCHEME FOR ELECTROHYDRAULIC FORMING USING HYBRID TAGUCHI-DATA ENVELOPMENT ANALYSIS-PARETO METHOD FOR ALUMINIUM ALLOY 1100 SHEETS IN AUTOMOTIVE PANELS

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ
This paper proposes a hybrid T-DEA-P (Taguchi-Data Envelopment Analysis-Pareto) method to optimise and rank parameters of the electrohydraulic forming process using the aluminium (AA1100) sheets for automotive panel application.
Olusola Michael Adeyemi, Boluvar Lathashankar, John Rajan, Swaminathan Jose, Sunday Ayoola Oke   +4 more
doaj   +1 more source

Kolmogorov-Burgers Model for Star Forming Turbulence

, 2001
The process of star formation in interstellar molecular clouds is believed to be controlled by driven supersonic magnetohydrodynamic turbulence. We suggest that in the inertial range such turbulence obeys the Kolmogorov law, while in the dissipative ...
Larson R. B., Larson R. B., Larson R. B., Smith M. D., Smith M. D., Stanislav Boldyrev   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Forme informes/Forme informi/ Shapeless forms

, 2023
La forme informe des villes, la liquidité de la société du XXIe siècle sont prises en compte par une théorie et une pratique de l'architecture qui trouvent dans l'espace, dans la relation entre les fragments, le surplus pour accueillir des termes tels que devenir et pluralisme, participation et interculturalisme, socialisation et transformation, é
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source