Results 211 to 220 of about 1,631,280 (354)
Process Design of Vinyl-Coated Metal Sheet Stamping for Prevention of Delamination and Wrinkling by DNN-Based Multi-Objective Optimization. [PDF]
Materials (Basel)Kim MG, Ryu JC, Lee CJ, Jang JS, Ko DC.
europepmc +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Effect of Strain Rate on the Formability Prediction of Cold-Rolled DX56D+Z100-M-C-O Steel Sheets. [PDF]
Materials (Basel)Novák V +4 more
europepmc +1 more source
Evaluation of deformation and forming limit of TRIP steel with microstructure
, 2002 Akira Ichihara, Yoshihiro TOMITA
openalex +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Multi-Scale Modeling in Forming Limits Analysis of SUS430/Al1050/TA1 Laminates: Integrating Crystal Plasticity Finite Element with M-K Theory. [PDF]
Materials (Basel)Li X, Liu C, Bai Y.
europepmc +1 more source
Understanding the Limits of Transnational NGO Power: Forms, Norms, and the Architecture
, 2022 Hans Peter Schmitz, G. E. Mitchell
openalex +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source