Results 151 to 160 of about 110,269 (254)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

A Green-Synthesized Zr-Tb Bimetallic MOF: Ratiometric Fluorescent Probe for Selective and Sensitive Detection of Ciprofloxacin. [PDF]

Molecules
Wang Y, Lu B, Li S, Ma C, Zou Y, Li G, Liu S.   +6 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Effect of Strain Rate on the Formability Prediction of Cold-Rolled DX56D+Z100-M-C-O Steel Sheets. [PDF]

Materials (Basel)
Novák V, Tatíček F, Stejskal O, Trzepieciński T, Żaba K.   +4 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Study on the influence of compaction energy and moisture content on the permeability and compression characteristics of granite-weathered soil. [PDF]

PLoS One
Lyu H, Wei D, Gu J, Fan L.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

A direct black-hole mass measurement in a little red dot at high redshift. [PDF]

Nature
Juodžbalis I, Marconcini C, D'Eugenio F, Maiolino R, Marconi A, Übler H, Scholtz J, Ji X, Jones GC, Perna M, Arribas S, Bennett JS, Bromm V, Bunker AJ, Carniani S, Charlot S, Cresci G, Dayal P, Egami E, Fabian A, Inayoshi K, Isobe Y, Ivey LR, Koudmani S, Laporte N, Liu B, Lyu J, Mazzolari G, Monty S, Parlanti E, Pérez-González PG, Robertson B, Schneider R, Sijacki D, Tacchella S, Trinca A, Valiante R, Volonteri M, Witstok J, Zhang S.   +39 more
europepmc   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Utility and Limitations of the Methyl Diaminobenzene-BODIPY Fluorescent Biosensor for Detecting Methylglyoxal in Cells. [PDF]

ACS Omega
Ponvattanaporn R, Le JP, Li Z, Rivero RJD, Mak JYW, Fairlie DP, McWilliam HEG, Hachani A, Corbett AJ, Patton T.   +9 more
europepmc   +1 more source